Interactor 1: M3K13 (O43283)
Mitogen-activated protein kinase kinase kinase 13 (EC 2.7.11.25) (Leucine zipper-bearing kinase) (Mixed lineage kinase) (MLK)
Gene: MAP3K13
Interactor 2: STAT3 (P40763)
Signal transducer and activator of transcription 3 (Acute-phase response factor)
Gene: STAT3
Species: Homo sapiens
Source: intact
Category: High-throughput
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.48 | 1.00 | 0.698 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 21988832 |
| Identification Methods | two hybrid, two hybrid array |
| Interaction Type | direct interaction, physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | PK_Tyr_Ser-Thr~SH2 |
| Common GO terms | GO:0005737 - cytoplasm GO:0019901 - protein kinase binding GO:0042803 - protein homodimerization activity GO:0051092 - positive regulation of NF-kappaB transcription factor activity |
| Homologous interactions | 5 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
