HitPredict

Interactor 1: SPIT2 (O43291)
Kunitz-type protease inhibitor 2 (Hepatocyte growth factor activator inhibitor type 2) (HAI-2) (Placental bikunin)
Gene: SPINT2

Interactor 2: FRMD5 (Q7Z6J6)
FERM domain-containing protein 5
Gene: FRMD5

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.60	0.667

Property	Details
Experiments	26186194, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0016020 - membrane GO:2000146 - negative regulation of cell motility
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 252 Hs			1 570
+	Hs
		395758 A4_HUMAN (136-184): 1.61e-20: 92.1: 55.10		E41L1_HUMAN (3-496): 7.52e-141: 431: 27.54
+	Hs
		204598 A4_HUMAN (136-184): 1.61e-20: 92.1: 55.10		E41L2_HUMAN (3-498): 2.96e-139: 430: 30.15
+	Hs
		394006 A4_HUMAN (136-184): 1.61e-20: 92.1: 55.10		EPB41_HUMAN (3-495): 9.68e-139: 425: 28.63
+	Mm
		517722 A4_MOUSE (136-184): 1.22e-20: 92.5: 55.10		E41L3_MOUSE (7-506): 7.43e-138: 424: 26.26
+	Hs
		395822 A4_HUMAN (136-184): 1.61e-20: 92.1: 55.10		E41L5_HUMAN (13-495): 1.07e-138: 421: 29.48
+	Hs
		395825 A4_HUMAN (136-184): 1.61e-20: 92.1: 55.10		E41LA_HUMAN (14-487): 5.96e-121: 374: 31.89