HitPredict

Interactor 1: SPIT2 (O43291)
Kunitz-type protease inhibitor 2 (Hepatocyte growth factor activator inhibitor type 2) (HAI-2) (Placental bikunin)
Gene: SPINT2

Interactor 2: VRK2 (Q86Y07)
Serine/threonine-protein kinase VRK2 (EC 2.7.11.1) (Vaccinia-related kinase 2)
Gene: VRK2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.60	0.667

Property	Details
Experiments	26186194, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 252 Hs			1 508
+	Hs
		987537 APLP2_HUMAN (31-132): 9.41e-25: 104: 22.55		MARK4_HUMAN (22-493): 6.04e-110: 345: 13.07
+	Hs
		395499 A4_HUMAN (136-184): 1.61e-20: 92.1: 55.10		MARK4_HUMAN (22-493): 6.04e-110: 345: 13.07
+	Hs
		394195 A4_HUMAN (136-184): 1.61e-20: 92.1: 55.10		AKT2_HUMAN (5-372): 9.14e-110: 336: 14.65
+	Hs
		394333 A4_HUMAN (136-184): 1.61e-20: 92.1: 55.10		KC1E_HUMAN (21-455): 3.27e-110: 335: 23.06
+	Hs
		394075 A4_HUMAN (136-184): 1.61e-20: 92.1: 55.10		KAPCA_HUMAN (17-370): 7.42e-110: 331: 13.45
+	Hs
		394125 A4_HUMAN (136-184): 1.61e-20: 92.1: 55.10		KAPCG_HUMAN (19-370): 1.35e-109: 331: 13.45
+	Hs
		822039 COSA1_HUMAN (129-185): 3.32e-20: 91.4: 33.33		KC1A_HUMAN (17-366): 5.32e-106: 321: 24.72
+	Hs
		394322 A4_HUMAN (136-184): 1.61e-20: 92.1: 55.10		KC1D_HUMAN (21-465): 9.4e-99: 305: 22.37
+	Hs
		395824 A4_HUMAN (136-184): 1.61e-20: 92.1: 55.10		KC1G1_HUMAN (24-392): 2.44e-97: 302: 23.47
+	Hs
		394517 A4_HUMAN (136-184): 1.61e-20: 92.1: 55.10		KC1G2_HUMAN (24-392): 2.53e-96: 299: 22.25