HitPredict

Interactor 1: SPIT2 (O43291)
Kunitz-type protease inhibitor 2 (Hepatocyte growth factor activator inhibitor type 2) (HAI-2) (Placental bikunin)
Gene: SPINT2

Interactor 2: TBC15 (Q8TC07)
TBC1 domain family member 15 (GTPase-activating protein RAB7) (GAP for RAB7) (Rab7-GAP)
Gene: TBC1D15

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.60	0.667

Property	Details
Experiments	26186194, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005576 - extracellular region GO:0005737 - cytoplasm
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 252 Hs			1 691
+	Hs
		199909 SPIT2_HUMAN (1-252): 4.61e-93: 275: 100.00		TBC9B_HUMAN (196-671): 5.6e-80: 279: 14.85
+	Hs
		394911 A4_HUMAN (136-184): 1.61e-20: 92.1: 55.10		TBC9B_HUMAN (196-671): 5.6e-80: 279: 14.85
+	Hs
		395367 A4_HUMAN (136-184): 1.61e-20: 92.1: 55.10		US6NL_HUMAN (292-690): 6.16e-82: 278: 19.04
+	Hs
		395151 A4_HUMAN (136-184): 1.61e-20: 92.1: 55.10		TBC21_HUMAN (310-626): 1.38e-86: 277: 27.39
+	Hs
		395112 A4_HUMAN (136-184): 1.61e-20: 92.1: 55.10		TB10C_HUMAN (288-667): 7.74e-81: 265: 16.10
+	Hs
		394823 A4_HUMAN (136-184): 1.61e-20: 92.1: 55.10		SGSM1_HUMAN (48-408): 1.34e-53: 201: 10.11