HitPredict

Interactor 1: TGFI1 (O43294)
Transforming growth factor beta-1-induced transcript 1 protein (Androgen receptor coactivator 55 kDa protein) (Androgen receptor-associated protein of 55 kDa) (Hydrogen peroxide-inducible clone 5 protein) (Hic-5)
Gene: TGFB1I1

Interactor 2: HSPB1 (P04792)
Heat shock protein beta-1 (HspB1) (28 kDa heat shock protein) (Estrogen-regulated 24 kDa protein) (Heat shock 27 kDa protein) (HSP 27) (Heat shock protein family B member 1) (Stress-responsive protein 27) (SRP27)
Gene: HSPB1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.72	0.60	0.661

Property	Details
Experiments	11546764, 25814672, 24831009
Identification Methods	two hybrid, affinity chromatography technology
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0005925 - focal adhesion GO:0030018 - Z disc
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 461 Hs			1 205
+	Hs
		200179 TGFI1_HUMAN (1-461): 8.49e-99: 305: 100.00		HSPB2_HUMAN (1-181): 2.16e-45: 150: 35.52
+	Hs
		388302 PAXI_HUMAN (345-461): 8.93e-37: 144: 34.19		HSPB1_HUMAN (1-205): 4.5e-80: 239: 100.00
+	Hs
		977981 ZNF92_HUMAN (81-390): 3.99e-51: 184: 8.90		HSPB8_HUMAN (1-180): 1.08e-42: 143: 37.17
+	Hs
		358708 ZNF3_HUMAN (81-293): 4.61e-30: 123: 7.87		CRYAA_HUMAN (21-195): 8.38e-54: 171: 38.42
+	Hs
		1344049 PDLI7_HUMAN (343-461): 4.25e-34: 134: 34.45		HSPB8_HUMAN (1-180): 1.08e-42: 143: 37.17
+	Hs
		1050648 FHL2_HUMAN (199-337): 2.52e-24: 103: 23.78		HSPB2_HUMAN (1-181): 2.16e-45: 150: 35.52
+	Hs
		358709 ZSC20_HUMAN (12-222): 1.33e-09: 62.5: 7.37		CRYAA_HUMAN (21-195): 8.38e-54: 171: 38.42