HitPredict

Interactor 1: TGFI1 (O43294)
Transforming growth factor beta-1-induced transcript 1 protein (Androgen receptor coactivator 55 kDa protein) (Androgen receptor-associated protein of 55 kDa) (Hydrogen peroxide-inducible clone 5 protein) (Hic-5)
Gene: TGFB1I1

Interactor 2: PTN12 (Q05209)
Tyrosine-protein phosphatase non-receptor type 12 (EC 3.1.3.48) (PTP-PEST) (Protein-tyrosine phosphatase G1) (PTPG1)
Gene: PTPN12

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.60	0.573

Property	Details
Experiments	10092676
Identification Methods	affinity chromatography technology, pull down, two hybrid
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0005925 - focal adhesion
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 461 Hs			1 780
+	Hs
		983496 ZFP2_HUMAN (14-367): 2.37e-95: 296: 8.38		PTN12_HUMAN (1-780): 0: 586: 100.00
+	Hs
		238955 LPXN_HUMAN (7-402): 5.82e-47: 168: 23.52		PTN12_HUMAN (1-780): 0: 586: 100.00
+	Mm
		728831 LPXN_MOUSE (16-403): 1.7e-51: 180: 24.37		PTN12_MOUSE (1-780): 0: 560: 83.10
+	Hs
		823374 PAXI_HUMAN (345-461): 8.93e-37: 144: 34.19		PTN12_HUMAN (1-780): 0: 586: 100.00
+	Hs
		441191 PAXI_HUMAN (345-461): 8.93e-37: 144: 34.19		PTPRC_HUMAN (13-678): 1.57e-143: 456: 19.30
+	Hs
		616910 PAXI_HUMAN (345-461): 8.93e-37: 144: 34.19		PTPRB_HUMAN (7-314): 1.22e-123: 410: 29.62
+	Hs
		823376 PAXI_HUMAN (345-461): 8.93e-37: 144: 34.19		PTN11_HUMAN (7-351): 1.65e-124: 387: 31.48
+	Hs
		665886 FHL3_HUMAN (250-461): 1.56e-20: 93.2: 27.78		PTN6_HUMAN (7-361): 1.95e-132: 407: 31.25
+	Hs
		150522 ABLM1_HUMAN (277-461): 3.32e-42: 161: 27.55		PTPRD_HUMAN (8-299): 1.81e-94: 325: 32.32
+	Hs
		146924 PAXI_HUMAN (345-461): 8.93e-37: 144: 34.19		PTPRT_HUMAN (8-296): 7.41e-63: 231: 25.93
+	Hs
		823400 PAXI_HUMAN (345-461): 8.93e-37: 144: 34.19		PTPRK_HUMAN (17-297): 1.82e-59: 221: 26.64
+	Hs
		563782 ZNF3_HUMAN (81-293): 4.61e-30: 123: 7.87		PTPRK_HUMAN (17-297): 1.82e-59: 221: 26.64
+	Hs
		617089 PAXI_HUMAN (345-461): 8.93e-37: 144: 34.19		PTPRG_HUMAN (8-299): 1.84e-52: 200: 24.50
+	Hs
		823408 PAXI_HUMAN (345-461): 8.93e-37: 144: 34.19		PTPRO_HUMAN (58-303): 3.31e-46: 180: 38.71
+	Hs
		823378 PAXI_HUMAN (345-461): 8.93e-37: 144: 34.19		PTPRJ_HUMAN (49-297): 6.23e-46: 179: 39.13
+	Mm
		93650 PAXI_MOUSE (345-461): 2.61e-36: 143: 34.19		PTPRO_MOUSE (58-303): 1.81e-43: 172: 38.31