Interactor 1: TGFI1 (O43294)
Transforming growth factor beta-1-induced transcript 1 protein (Androgen receptor coactivator 55 kDa protein) (Androgen receptor-associated protein of 55 kDa) (Hydrogen peroxide-inducible clone 5 protein) (Hic-5)
Gene: TGFB1I1

Interactor 2: SMAD4 (Q13485)
Mothers against decapentaplegic homolog 4 (MAD homolog 4) (Mothers against DPP homolog 4) (Deletion target in pancreatic carcinoma 4) (SMAD family member 4) (SMAD 4) (Smad4) (hSMAD4)
Gene: SMAD4

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 0.60 0.479

The method score is based on:

Property Details
Experiments 15561701
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005829 - cytosol
GO:0008285 - negative regulation of cell population proliferation
GO:0010718 - positive regulation of epithelial to mesenchymal transition
GO:0030511 - positive regulation of transforming growth factor beta receptor signaling pathway
GO:0045893 - positive regulation of DNA-templated transcription
and 2 others

more...

Homologous interactions 13

Homologous interactions

Color coding for hit scores

1 461
Hs

1 552
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024