HitPredict

Interactor 1: TGFI1 (O43294)
Transforming growth factor beta-1-induced transcript 1 protein (Androgen receptor coactivator 55 kDa protein) (Androgen receptor-associated protein of 55 kDa) (Hydrogen peroxide-inducible clone 5 protein) (Hic-5)
Gene: TGFB1I1

Interactor 2: CUL3 (Q13618)
Cullin-3 (CUL-3)
Gene: CUL3

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35563538
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0016055 - Wnt signaling pathway
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 461 Hs			1 768
+	Hs
		549161 ZN250_HUMAN (180-459): 5.77e-96: 301: 14.24		CUL3_HUMAN (1-768): 0: 951: 100.00
+	Hs
		1042799 ZN229_HUMAN (13-371): 2.36e-91: 296: 9.04		CUL3_HUMAN (1-768): 0: 951: 100.00
+	Hs
		1041813 ZN544_HUMAN (19-310): 1.8e-69: 236: 9.12		CUL3_HUMAN (1-768): 0: 951: 100.00
+	Hs
		1041826 Z585A_HUMAN (15-274): 4.7e-55: 197: 8.40		CUL3_HUMAN (1-768): 0: 951: 100.00
+	Hs
		1041578 ZN268_HUMAN (193-459): 1.63e-53: 194: 9.94		CUL3_HUMAN (1-768): 0: 951: 100.00
+	Hs
		1042144 ZN480_HUMAN (294-460): 3.82e-48: 174: 14.44		CUL3_HUMAN (1-768): 0: 951: 100.00
+	Hs
		565092 ZNF7_HUMAN (18-250): 3.26e-44: 166: 3.88		CUL3_HUMAN (1-768): 0: 951: 100.00
+	Hs
		150567 ABLM1_HUMAN (277-461): 3.32e-42: 161: 27.55		CUL3_HUMAN (1-768): 0: 951: 100.00
+	Hs
		1042314 ZN583_HUMAN (81-338): 2.4e-42: 159: 9.54		CUL3_HUMAN (1-768): 0: 951: 100.00
+	Hs
		1042336 ZN300_HUMAN (20-225): 9.5e-41: 155: 8.21		CUL3_HUMAN (1-768): 0: 951: 100.00
+	Hs
		73009 ZN879_HUMAN (20-221): 8.36e-41: 155: 5.45		CUL3_HUMAN (1-768): 0: 951: 100.00
+	Hs
		846676 ZNF84_HUMAN (19-225): 1.1e-39: 153: 5.31		CUL3_HUMAN (1-768): 0: 951: 100.00
+	Hs
		823390 PAXI_HUMAN (345-461): 8.93e-37: 144: 34.19		CUL3_HUMAN (1-768): 0: 951: 100.00
+	Hs
		1042371 ZN184_HUMAN (13-222): 6.16e-35: 140: 4.76		CUL3_HUMAN (1-768): 0: 951: 100.00
+	Hs
		1042618 PDLI7_HUMAN (343-461): 4.25e-34: 134: 34.45		CUL3_HUMAN (1-768): 0: 951: 100.00
+	Hs
		1041998 ZN100_HUMAN (81-302): 2.64e-29: 122: 8.89		CUL3_HUMAN (1-768): 0: 951: 100.00
+	Hs
		1042010 ZN567_HUMAN (19-195): 3.06e-26: 113: 5.65		CUL3_HUMAN (1-768): 0: 951: 100.00
+	Hs
		1041738 ZN569_HUMAN (19-194): 1.97e-24: 108: 4.55		CUL3_HUMAN (1-768): 0: 951: 100.00
+	Hs
		200252 ZN264_HUMAN (132-296): 1.09e-23: 105: 7.78		CUL3_HUMAN (1-768): 0: 951: 100.00
+	Hs
		816243 LIMS1_HUMAN (212-340): 4.04e-24: 104: 24.69		CUL3_HUMAN (1-768): 0: 951: 100.00