HitPredict

Interactor 1: SRGP3 (O43295)
SLIT-ROBO Rho GTPase-activating protein 3 (srGAP3) (Mental disorder-associated GAP) (Rho GTPase-activating protein 14) (WAVE-associated Rac GTPase-activating protein) (WRP)
Gene: SRGAP3

Interactor 2: HD (P42858)
Huntingtin (Huntington disease protein) (HD protein) [Cleaved into: Huntingtin, myristoylated N-terminal fragment]
Gene: HTT

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.34	0.60	0.457

Property	Details
Experiments	17500595
Identification Methods	two hybrid
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 1099 Hs			1 3142
+	Hs
		791711 SRGP1_HUMAN (1-1087): 0: 708: 67.83		HD_HUMAN (1-3142): 0: 5724: 100.00
+	Hs
		253326 SRGP2_HUMAN (1-1087): 0: 675: 57.36		HD_HUMAN (1-3142): 0: 5724: 100.00
+	Mm
		103089 SRGP3_MOUSE (1-1099): 0: 794: 98.54		G3X9H5_MOUSE (81-3142): 0: 5479: 91.19
+	Hs
		791621 RHG29_HUMAN (44-1085): 3.59e-108: 368: 15.42		HD_HUMAN (1-3142): 0: 5724: 100.00
+	Hs
		791742 Q8IXS7_HUMAN (121-441): 6.51e-102: 326: 99.69		HD_HUMAN (1-3142): 0: 5724: 100.00
+	Hs
		791753 RHG24_HUMAN (520-701): 3.97e-23: 108: 32.09		HD_HUMAN (1-3142): 0: 5724: 100.00