Interactor 1: SRGP3 (O43295)
SLIT-ROBO Rho GTPase-activating protein 3 (srGAP3) (Mental disorder-associated GAP) (Rho GTPase-activating protein 14) (WAVE-associated Rac GTPase-activating protein) (WRP)
Gene: SRGAP3
Interactor 2: GRB2 (P62993)
Growth factor receptor-bound protein 2 (Adapter protein GRB2) (Protein Ash) (SH2/SH3 adapter GRB2)
Gene: GRB2
Species: Homo sapiens
Source: mint
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.52 | 1.00 | 0.724 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 25819436 |
| Identification Methods | anti tag coimmunoprecipitation, isothermal titration calorimetry |
| Interaction Type | physical association, direct interaction |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | SH2~SH3_1, SH3_1~SH3_1 |
| Common GO terms | GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0007165 - signal transduction |
| Homologous interactions | 20 |
Homologous interactions (Top 20)
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
