HitPredict

Interactor 1: LRRT2 (O43300)
Leucine-rich repeat transmembrane neuronal protein 2 (Leucine-rich repeat neuronal 2 protein)
Gene: LRRTM2

Interactor 2: CNPY4 (Q8N129)
Protein canopy homolog 4
Gene: CNPY4

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.50	0.609

Property	Details
Experiments	26186194, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 516 Hs			1 248
+	Hs
		1201399 LRRT4_HUMAN (28-516): 6.66e-110: 340: 43.41		CNPY4_HUMAN (1-248): 8.6e-128: 363: 100.00
+	Hs
		200348 LRRT2_HUMAN (1-516): 2.31e-111: 341: 100.00		CNPY3_HUMAN (27-205): 2.9e-96: 284: 50.28
+	Hs
		1201401 LRRT4_HUMAN (28-516): 6.66e-110: 340: 43.41		CNPY3_HUMAN (27-205): 2.9e-96: 284: 50.28
+	Hs
		1230126 LRIG1_HUMAN (11-372): 6.24e-72: 249: 23.80		CNPY4_HUMAN (1-248): 8.6e-128: 363: 100.00
+	Hs
		175594 CHAD_HUMAN (34-364): 1.55e-74: 241: 29.34		CNPY4_HUMAN (1-248): 8.6e-128: 363: 100.00
+	Hs
		1291077 LIGO1_HUMAN (31-360): 1.25e-85: 278: 25.39		CNPY3_HUMAN (27-205): 2.9e-96: 284: 50.28
+	Hs
		1294954 LRIG1_HUMAN (11-372): 6.24e-72: 249: 23.80		CNPY3_HUMAN (27-205): 2.9e-96: 284: 50.28
+	Hs
		1311698 LRC4C_HUMAN (31-368): 4.63e-74: 248: 23.10		CNPY3_HUMAN (27-205): 2.9e-96: 284: 50.28
+	Hs
		1185469 LIGO2_HUMAN (3-363): 5.36e-74: 247: 22.41		CNPY3_HUMAN (27-205): 2.9e-96: 284: 50.28
+	Hs
		175595 CHAD_HUMAN (34-364): 1.55e-74: 241: 29.34		CNPY3_HUMAN (27-205): 2.9e-96: 284: 50.28
+	Hs
		1201410 LRRT3_HUMAN (9-167): 5.67e-19: 91.9: 20.86		CNPY4_HUMAN (1-248): 8.6e-128: 363: 100.00
+	Hs
		1230129 RXFP1_HUMAN (134-311): 6.84e-13: 73.2: 31.84		CNPY4_HUMAN (1-248): 8.6e-128: 363: 100.00
+	Hs
		1230128 LGR4_HUMAN (48-307): 3.12e-11: 68.2: 28.07		CNPY4_HUMAN (1-248): 8.6e-128: 363: 100.00
+	Hs
		1199487 LRRT1_HUMAN (11-215): 1.46e-24: 108: 20.00		CNPY3_HUMAN (27-205): 2.9e-96: 284: 50.28
+	Hs
		728889 ALS_HUMAN (62-311): 1.39e-22: 103: 28.52		CNPY3_HUMAN (27-205): 2.9e-96: 284: 50.28
+	Hs
		1201411 LRRT3_HUMAN (9-167): 5.67e-19: 91.9: 20.86		CNPY3_HUMAN (27-205): 2.9e-96: 284: 50.28
+	Hs
		299582 LRIG2_HUMAN (85-311): 8.5e-17: 85.9: 30.16		CNPY3_HUMAN (27-205): 2.9e-96: 284: 50.28
+	Hs
		1311697 RXFP1_HUMAN (134-311): 6.84e-13: 73.2: 31.84		CNPY3_HUMAN (27-205): 2.9e-96: 284: 50.28
+	Hs
		265897 LGR5_HUMAN (66-294): 3.2e-10: 64.7: 30.13		CNPY3_HUMAN (27-205): 2.9e-96: 284: 50.28