HitPredict

Interactor 1: ADCY6 (O43306)
Adenylate cyclase type 6 (EC 4.6.1.1) (ATP pyrophosphate-lyase 6) (Adenylate cyclase type VI) (Adenylyl cyclase 6) (Ca(2+)-inhibitable adenylyl cyclase)
Gene: ADCY6

Interactor 2: LEG3 (P17931)
Galectin-3 (Gal-3) (35 kDa lectin) (Carbohydrate-binding protein 35) (CBP 35) (Galactose-specific lectin 3) (Galactoside-binding protein) (GALBP) (IgE-binding protein) (L-31) (Laminin-binding protein) (Lectin L-29) (Mac-2 antigen)
Gene: LGALS3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.60	0.667

Property	Details
Experiments	26186194, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0016020 - membrane
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 1168 Hs			1 250
+	Hs
		121058 ADCY6_HUMAN (1-1168): 0: 1463: 100.00		LEG8_HUMAN (105-245): 4.74e-39: 139: 36.11
+	Hs
		200741 ADCY6_HUMAN (1-1168): 0: 1463: 100.00		LEG9B_HUMAN (108-249): 5.78e-38: 137: 37.67
+	Hs
		229538 ADCY3_HUMAN (98-1164): 0: 1008: 34.46		LEG3_HUMAN (1-250): 3.29e-96: 283: 100.00
+	Hs
		572308 ADCY8_HUMAN (108-625): 5.4e-56: 214: 20.14		LEG3_HUMAN (1-250): 3.29e-96: 283: 100.00
+	Hs
		235334 ADCY9_HUMAN (657-1164): 6.37e-48: 189: 17.49		LEG3_HUMAN (1-250): 3.29e-96: 283: 100.00
+	Hs
		121062 ADCY9_HUMAN (657-1164): 6.37e-48: 189: 17.49		LEG8_HUMAN (105-245): 4.74e-39: 139: 36.11
+	Hs
		235376 ADCY9_HUMAN (657-1164): 6.37e-48: 189: 17.49		LEG9B_HUMAN (108-249): 5.78e-38: 137: 37.67