HitPredict

Interactor 1: ADCY6 (O43306)
Adenylate cyclase type 6 (EC 4.6.1.1) (ATP pyrophosphate-lyase 6) (Adenylate cyclase type VI) (Adenylyl cyclase 6) (Ca(2+)-inhibitable adenylyl cyclase)
Gene: ADCY6

Interactor 2: ANKY2 (Q8IV38)
Ankyrin repeat and MYND domain-containing protein 2
Gene: ANKMY2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005929 - cilium GO:0046872 - metal ion binding
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 1168 Hs			1 441
+	Hs
		995732 ADCY2_HUMAN (133-1163): 0: 1036: 37.12		ANKY2_HUMAN (1-441): 8.31e-108: 327: 100.00
+	Hs
		229555 ADCY3_HUMAN (98-1164): 0: 1008: 34.46		ANKY2_HUMAN (1-441): 8.31e-108: 327: 100.00
+	Hs
		969052 GCYB1_HUMAN (268-532): 1.57e-69: 247: 28.10		ANKY2_HUMAN (1-441): 8.31e-108: 327: 100.00
+	Hs
		768546 ADCY8_HUMAN (108-625): 5.4e-56: 214: 20.14		ANKY2_HUMAN (1-441): 8.31e-108: 327: 100.00
+	Hs
		235387 ADCY9_HUMAN (657-1164): 6.37e-48: 189: 17.49		ANKY2_HUMAN (1-441): 8.31e-108: 327: 100.00