HitPredict

Interactor 1: VIP2 (O43314)
Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2 (EC 2.7.4.24) (Diphosphoinositol pentakisphosphate kinase 2) (Histidine acid phosphatase domain-containing protein 1) (InsP6 and PP-IP5 kinase 2) (VIP1 homolog 2) (hsVIP2)
Gene: PPIP5K2

Interactor 2: 1433T (P27348)
14-3-3 protein theta (14-3-3 protein T-cell) (14-3-3 protein tau) (Protein HS1)
Gene: YWHAQ

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.60	0.60	0.601

Property	Details
Experiments	33961781, 28514442
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 1243 Hs			1 245
+	Hs
		200998 VIP2_HUMAN (1-1243): 0: 2077: 100.00		1433E_HUMAN (2-243): 1.31e-144: 406: 63.53
+	Hs
		201001 VIP2_HUMAN (1-1243): 0: 2077: 100.00		1433Z_HUMAN (1-245): 1.75e-141: 397: 79.59
+	Hs
		200981 VIP2_HUMAN (1-1243): 0: 2077: 100.00		1433B_HUMAN (1-242): 5.01e-139: 391: 81.82
+	Hs
		200982 VIP2_HUMAN (1-1243): 0: 2077: 100.00		1433S_HUMAN (1-236): 9.86e-108: 312: 71.85
+	Hs
		201006 VIP2_HUMAN (1-1243): 0: 2077: 100.00		1433F_HUMAN (2-242): 7.16e-106: 307: 71.43
+	Hs
		200997 VIP2_HUMAN (1-1243): 0: 2077: 100.00		1433G_HUMAN (1-242): 5.48e-105: 305: 70.33
+	Hs
		904726 VIP1_HUMAN (43-1222): 0: 1779: 68.56		1433G_HUMAN (1-242): 5.48e-105: 305: 70.33
+	Ce
		954354 VIP1_CAEEL (28-1053): 0: 1258: 49.63		14332_CAEEL (3-241): 2.09e-116: 334: 77.41
+	Ce
		785022 VIP1_CAEEL (28-1053): 0: 1258: 49.63		14331_CAEEL (5-236): 1.61e-109: 317: 77.59