Interactor 1: M3K7 (O43318)
Mitogen-activated protein kinase kinase kinase 7 (EC 2.7.11.25) (Transforming growth factor-beta-activated kinase 1) (TGF-beta-activated kinase 1)
Gene: MAP3K7
Interactor 2: M3K7 (O43318)
Mitogen-activated protein kinase kinase kinase 7 (EC 2.7.11.25) (Transforming growth factor-beta-activated kinase 1) (TGF-beta-activated kinase 1)
Gene: MAP3K7
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
Method score | Annotation score | Interaction score |
---|---|---|
0.96 | 1.00 | 0.982 |
The method score is based on:
Property | Details |
---|---|
Experiments | 12624112, 27497262, 31980649, 9556573, 34490261, 12482967, 9742107, 19232515, 20538596, 10702308, 21817100, 15590691, 14743216 |
Identification Methods | enzymatic study, affinity chromatography technology, pull down, in-gel kinase assay, tandem affinity purification |
Interaction Type | direct interaction, physical association, phosphorylation reaction |
The annotation score is based on:
Property | Details |
---|---|
Interacting Pfam domains | PK_Tyr_Ser-Thr~PK_Tyr_Ser-Thr |
Common GO terms | GO:0000165 - MAPK cascade GO:0000287 - magnesium ion binding GO:0001223 - transcription coactivator binding GO:0002223 - stimulatory C-type lectin receptor signaling pathway GO:0002726 - positive regulation of T cell cytokine production and 57 others more... |
Homologous interactions | 18 |
Homologous interactions
Color coding for hit scores
Service provided by Combinatics, Japan
Last updated: 15 Jul 2024