HitPredict

Interactor 1: M3K7 (O43318)
Mitogen-activated protein kinase kinase kinase 7 (EC 2.7.11.25) (Transforming growth factor-beta-activated kinase 1) (TGF-beta-activated kinase 1)
Gene: MAP3K7

Interactor 2: KERA (O60938)
Keratocan (KTN) (Keratan sulfate proteoglycan keratocan)
Gene: KERA

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.80	0.726

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	LRR_8~PK_Tyr_Ser-Thr
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 606 Hs			1 352
+	At
		83675 Y5457_ARATH (4-325): 1.36e-121: 374: 22.06		RGI5_ARATH (2-322): 4.46e-41: 155: 18.37
+	At
		95380 F4I065_ARATH (3-316): 1.48e-122: 385: 22.32		TDR_ARATH (1-318): 6.73e-37: 143: 17.51
+	At
		84130 Y2289_ARATH (12-316): 1.26e-122: 385: 23.40		Y4361_ARATH (15-349): 1.12e-36: 142: 19.10
+	At
		84729 F4I065_ARATH (3-316): 1.48e-122: 385: 22.32		Y4361_ARATH (15-349): 1.12e-36: 142: 19.10
+	At
		84139 Y2289_ARATH (12-316): 1.26e-122: 385: 23.40		SKM1_ARATH (19-276): 1.31e-34: 136: 20.97
+	At
		95366 F4I065_ARATH (3-316): 1.48e-122: 385: 22.32		RGI4_ARATH (50-349): 2.13e-34: 136: 22.05
+	At
		84454 Y5457_ARATH (4-325): 1.36e-121: 374: 22.06		GSO1_ARATH (1-331): 2.51e-37: 144: 19.08
+	At
		85027 Y5457_ARATH (4-325): 1.36e-121: 374: 22.06		TDR_ARATH (1-318): 6.73e-37: 143: 17.51
+	At
		84727 Y5457_ARATH (4-325): 1.36e-121: 374: 22.06		Y4361_ARATH (15-349): 1.12e-36: 142: 19.10
+	At
		85004 Y5457_ARATH (4-325): 1.36e-121: 374: 22.06		SKM1_ARATH (19-276): 1.31e-34: 136: 20.97
+	At
		85030 Y5457_ARATH (4-325): 1.36e-121: 374: 22.06		PXL1_ARATH (1-284): 2.31e-34: 135: 17.24
+	At
		84208 Y2289_ARATH (12-316): 1.26e-122: 385: 23.40		BRL2_ARATH (2-278): 6.22e-30: 123: 16.57
+	At
		84185 Y2289_ARATH (12-316): 1.26e-122: 385: 23.40		IRK_ARATH (1-260): 8.31e-30: 122: 15.33
+	At
		95398 F4I065_ARATH (3-316): 1.48e-122: 385: 22.32		Q9XGZ2_ARATH (1-284): 1.43e-26: 113: 14.68
+	At
		85045 Y5457_ARATH (4-325): 1.36e-121: 374: 22.06		IRK_ARATH (1-260): 8.31e-30: 122: 15.33
+	At
		85038 Y5457_ARATH (4-325): 1.36e-121: 374: 22.06		Y1571_ARATH (195-352): 1.07e-23: 104: 18.18
+	At
		84147 Y2289_ARATH (12-316): 1.26e-122: 385: 23.40		ERL2_ARATH (1-193): 4.8e-18: 87.6: 15.00
+	At
		85102 F4I065_ARATH (3-316): 1.48e-122: 385: 22.32		RGI2_ARATH (183-350): 7.48e-18: 86.8: 16.13
+	At
		95392 F4I065_ARATH (3-316): 1.48e-122: 385: 22.32		BAME2_ARATH (12-189): 1.12e-16: 83.4: 19.46
+	At
		85010 Y5457_ARATH (4-325): 1.36e-121: 374: 22.06		ERL2_ARATH (1-193): 4.8e-18: 87.6: 15.00