Interactor 1: M3K7 (O43318)
Mitogen-activated protein kinase kinase kinase 7 (EC 2.7.11.25) (Transforming growth factor-beta-activated kinase 1) (TGF-beta-activated kinase 1)
Gene: MAP3K7
Interactor 2: TAB1 (Q15750)
TGF-beta-activated kinase 1 and MAP3K7-binding protein 1 (Mitogen-activated protein kinase kinase kinase 7-interacting protein 1) (TGF-beta-activated kinase 1-binding protein 1) (TAK1-binding protein 1)
Gene: TAB1
Species: Homo sapiens
Source: mint
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.99 | 0.60 | 0.771 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 24912525, 26432169, 12624112, 27468689, 28507161, 14670075, 32410369, 10838074, 33717111, 35271311, 32707033, 36736316, 19026643, 21903422, 20200282, 15590691, 18456659, 22167179, 12242293, 8638164 and 19 others
more... |
| Identification Methods | affinity chromatography technology, two hybrid, enzymatic study, tandem affinity purification, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation, protein kinase assay, pull down |
| Interaction Type | physical association, direct interaction, association, phosphorylation reaction |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | - |
| Common GO terms | GO:0005737 - cytoplasm GO:0005789 - endoplasmic reticulum membrane GO:0005829 - cytosol GO:0007179 - transforming growth factor beta receptor signaling pathway GO:0010008 - endosome membrane and 1 others more... |
| Homologous interactions | 7 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
