Interactor 1: M3K7 (O43318)
Mitogen-activated protein kinase kinase kinase 7 (EC 2.7.11.25) (Transforming growth factor-beta-activated kinase 1) (TGF-beta-activated kinase 1)
Gene: MAP3K7

Interactor 2: TAB2 (Q9NYJ8)
TGF-beta-activated kinase 1 and MAP3K7-binding protein 2 (Mitogen-activated protein kinase kinase kinase 7-interacting protein 2) (TAK1-binding protein 2) (TAB-2) (TGF-beta-activated kinase 1-binding protein 2)
Gene: TAB2

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.99 0.60 0.771

The method score is based on:

Property Details
Experiments 25642820, 27426733, 14670075, 30348973, 31127032, 32410369, 32303555, 10882101, 33717111, 34535633, 34799425, 35217833, 36130827, 14633987, 16603398, 21903422, 18021073, 22081109, 12242293, 17384642 and 25 others

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Identification Methods two hybrid, affinity chromatography technology, pull down, tandem affinity purification, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0005886 - plasma membrane
GO:0006954 - inflammatory response
GO:0010008 - endosome membrane
and 2 others

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Homologous interactions 4

Homologous interactions

Color coding for hit scores

1 606
Hs

1 693
+ Rn
+ Mm
+ Hs
+ Mm

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Last updated: 15 Jul 2024