Interactor 1: M3K7 (O43318)
Mitogen-activated protein kinase kinase kinase 7 (EC 2.7.11.25) (Transforming growth factor-beta-activated kinase 1) (TGF-beta-activated kinase 1)
Gene: MAP3K7

Interactor 2: NLK (Q9UBE8)
Serine/threonine-protein kinase NLK (EC 2.7.11.24) (Nemo-like kinase) (Protein LAK1)
Gene: NLK

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.57 1.00 0.759

The method score is based on:

Property Details
Experiments 20194509, 15764709
Identification Methods affinity chromatography technology, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains PK_Tyr_Ser-Thr~Pkinase
Common GO terms GO:0000287 - magnesium ion binding
GO:0004674 - protein serine/threonine kinase activity
GO:0004707 - MAP kinase activity
GO:0005524 - ATP binding
GO:0005634 - nucleus
and 6 others

more...

Homologous interactions 15

Homologous interactions

Color coding for hit scores

1 606
Hs

1 527
+ At
+ At
+ At
+ At
+ At
+ At
+ At
+ At
+ At
+ Rn
+ At
+ At
+ Hs
+ Hs
+ Hs

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Last updated: 15 Jul 2024