HitPredict

Interactor 1: MCA3 (O43324)
Eukaryotic translation elongation factor 1 epsilon-1 (Aminoacyl tRNA synthetase complex-interacting multifunctional protein 3) (Elongation factor p18) (Multisynthase complex auxiliary component p18)
Gene: EEF1E1

Interactor 2: RAF1 (P04049)
RAF proto-oncogene serine/threonine-protein kinase (EC 2.7.11.1) (Proto-oncogene c-RAF) (cRaf) (Raf-1)
Gene: RAF1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.60	0.60	0.601

Property	Details
Experiments	26496610, 37045861
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0008285 - negative regulation of cell population proliferation
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 174 Hs			1 648
+	Hs
		373711 EF1G_HUMAN (26-167): 3.61e-37: 134: 22.09		RAF1_HUMAN (1-648): 0: 652: 100.00
+	Hs
		373541 SYEP_HUMAN (12-171): 1.32e-33: 127: 21.47		RAF1_HUMAN (1-648): 0: 652: 100.00
+	Hs
		373710 SYVC_HUMAN (28-164): 5.38e-20: 88.2: 25.32		RAF1_HUMAN (1-648): 0: 652: 100.00
+	Hs
		201559 MCA3_HUMAN (1-174): 5.33e-55: 173: 100.00		ARAF_HUMAN (45-646): 4.63e-169: 497: 59.28
+	Hs
		430856 SYEP_HUMAN (12-171): 1.32e-33: 127: 21.47		BRAF_HUMAN (39-647): 1.29e-170: 507: 55.88
+	Hs
		488576 EF1G_HUMAN (26-167): 3.61e-37: 134: 22.09		ARAF_HUMAN (45-646): 4.63e-169: 497: 59.28
+	Hs
		430849 SYEP_HUMAN (12-171): 1.32e-33: 127: 21.47		ARAF_HUMAN (45-646): 4.63e-169: 497: 59.28
+	At
		790223 GSTFA_ARATH (5-164): 3.86e-38: 131: 18.09		BAK1_ARATH (77-647): 6.91e-163: 482: 17.30
+	Hs
		412027 SYVC_HUMAN (28-164): 5.38e-20: 88.2: 25.32		FYN_HUMAN (337-607): 2.33e-103: 326: 34.55