Interactor 1: RIPK2 (O43353)
Receptor-interacting serine/threonine-protein kinase 2 (EC 2.7.11.1) (CARD-containing interleukin-1 beta-converting enzyme-associated kinase) (CARD-containing IL-1 beta ICE-kinase) (RIP-like-interacting CLARP kinase) (Receptor-interacting protein 2) (RIP-2) (Tyrosine-protein kinase RIPK2) (EC 2.7.10.2)
Gene: RIPK2
Interactor 2: TNR5 (P25942)
Tumor necrosis factor receptor superfamily member 5 (B-cell surface antigen CD40) (Bp50) (CD40L receptor) (CDw40) (CD antigen CD40)
Gene: CD40
Species: Homo sapiens
Source: biogrid
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.38 | 0.60 | 0.479 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 9642260 |
| Identification Methods | affinity chromatography technology |
| Interaction Type | physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | - |
| Common GO terms | GO:0005886 - plasma membrane GO:0006954 - inflammatory response GO:0032735 - positive regulation of interleukin-12 production GO:0043123 - positive regulation of canonical NF-kappaB signal transduction GO:0045944 - positive regulation of transcription by RNA polymerase II and 1 others more... |
| Homologous interactions | 10 |
Homologous interactions
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
