Interactor 1: RIPK2 (O43353)
Receptor-interacting serine/threonine-protein kinase 2 (EC 2.7.11.1) (CARD-containing interleukin-1 beta-converting enzyme-associated kinase) (CARD-containing IL-1 beta ICE-kinase) (RIP-like-interacting CLARP kinase) (Receptor-interacting protein 2) (RIP-2) (Tyrosine-protein kinase RIPK2) (EC 2.7.10.2)
Gene: RIPK2

Interactor 2: TRAF4 (Q9BUZ4)
TNF receptor-associated factor 4 (EC 2.3.2.27) (Cysteine-rich domain associated with RING and Traf domains protein 1) (Metastatic lymph node gene 62 protein) (MLN 62) (RING finger protein 83)
Gene: TRAF4

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 0.60 0.479

The method score is based on:

Property Details
Experiments 21097508
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0005856 - cytoskeleton
GO:0005886 - plasma membrane
GO:0006915 - apoptotic process
and 2 others

more...

Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 540
Hs

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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024