Interactor 1: RIPK2 (O43353)
Receptor-interacting serine/threonine-protein kinase 2 (EC 2.7.11.1) (CARD-containing interleukin-1 beta-converting enzyme-associated kinase) (CARD-containing IL-1 beta ICE-kinase) (RIP-like-interacting CLARP kinase) (Receptor-interacting protein 2) (RIP-2) (Tyrosine-protein kinase RIPK2) (EC 2.7.10.2)
Gene: RIPK2
Interactor 2: NOD1 (Q9Y239)
Nucleotide-binding oligomerization domain-containing protein 1 (hNod1) (Caspase recruitment domain-containing protein 4)
Gene: NOD1
Species: Homo sapiens
Source: mint
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.91 | 1.00 | 0.956 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 23300079, 10329646, 29997244, 16517750, 19667203, 19337385, 17054981 |
| Identification Methods | pull down, affinity chromatography technology, fluorescent resonance energy transfer, anti tag coimmunoprecipitation, two hybrid, coimmunoprecipitation |
| Interaction Type | direct interaction, physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | CARD~CARD |
| Common GO terms | GO:0005524 - ATP binding GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0006915 - apoptotic process and 24 others more... |
| Homologous interactions | 10 |
Homologous interactions
Color coding for hit scores 
|
|
|||||||||||||
| + | Hs |   |
|
|||||||||||
| + | Hs |  |
|
|||||||||||
| + | Hs | |
|
|||||||||||
| + | Mm | |
|
|||||||||||
| + | At | |
|
|||||||||||
| + | At | |
|
|||||||||||
| + | At | |
|
|||||||||||
| + | At | |
|
|||||||||||
| + | At | |
|
|||||||||||
| + | At | |
|
|||||||||||
Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
