HitPredict

Interactor 1: HNRPR (O43390)
Heterogeneous nuclear ribonucleoprotein R (hnRNP R)
Gene: HNRNPR

Interactor 2: CUL3 (Q13618)
Cullin-3 (CUL-3)
Gene: CUL3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	35563538, 21145461
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 633 Hs			1 768
+	Hs
		235848 HNRPQ_HUMAN (3-633): 1.1e-116: 363: 78.17		CUL3_HUMAN (1-768): 0: 951: 100.00
+	Mm
		1186462 HNRPQ_MOUSE (3-633): 2.52e-116: 362: 78.17		CUL3_MOUSE (1-768): 0: 949: 99.48
+	Hs
		202156 HNRPR_HUMAN (1-633): 1.8e-124: 383: 100.00		CUL4B_HUMAN (5-768): 0: 779: 36.77
+	Hs
		235849 HNRPQ_HUMAN (3-633): 1.1e-116: 363: 78.17		CUL4B_HUMAN (5-768): 0: 779: 36.77
+	Hs
		202153 HNRPR_HUMAN (1-633): 1.8e-124: 383: 100.00		CUL1_HUMAN (18-768): 0: 707: 30.57
+	Hs
		235846 HNRPQ_HUMAN (3-633): 1.1e-116: 363: 78.17		CUL1_HUMAN (18-768): 0: 707: 30.57
+	Hs
		1031317 PABP4_HUMAN (69-235): 3.94e-23: 106: 14.44		CUL3_HUMAN (1-768): 0: 951: 100.00
+	Hs
		202154 HNRPR_HUMAN (1-633): 1.8e-124: 383: 100.00		CUL2_HUMAN (30-768): 0: 672: 26.17
+	Hs
		516505 PABP1_HUMAN (69-235): 3.67e-20: 96.6: 16.20		CUL3_HUMAN (1-768): 0: 951: 100.00
+	Hs
		235847 HNRPQ_HUMAN (3-633): 1.1e-116: 363: 78.17		CUL2_HUMAN (30-768): 0: 672: 26.17
+	Hs
		202240 HNRPR_HUMAN (1-633): 1.8e-124: 383: 100.00		CUL5_HUMAN (25-768): 0: 597: 23.77
+	Hs
		235993 HNRPQ_HUMAN (3-633): 1.1e-116: 363: 78.17		CUL5_HUMAN (25-768): 0: 597: 23.77
+	Hs
		1031318 PABP4_HUMAN (69-235): 3.94e-23: 106: 14.44		CUL4A_HUMAN (10-768): 0: 791: 38.32
+	Hs
		516506 PABP1_HUMAN (69-235): 3.67e-20: 96.6: 16.20		CUL4A_HUMAN (10-768): 0: 791: 38.32
+	Hs
		1031319 PABP4_HUMAN (69-235): 3.94e-23: 106: 14.44		CUL4B_HUMAN (5-768): 0: 779: 36.77
+	Hs
		1031315 PABP4_HUMAN (69-235): 3.94e-23: 106: 14.44		CUL1_HUMAN (18-768): 0: 707: 30.57
+	Hs
		516503 PABP1_HUMAN (69-235): 3.67e-20: 96.6: 16.20		CUL1_HUMAN (18-768): 0: 707: 30.57
+	Hs
		1031316 PABP4_HUMAN (69-235): 3.94e-23: 106: 14.44		CUL2_HUMAN (30-768): 0: 672: 26.17
+	Hs
		516504 PABP1_HUMAN (69-235): 3.67e-20: 96.6: 16.20		CUL2_HUMAN (30-768): 0: 672: 26.17
+	Hs
		1031416 PABP4_HUMAN (69-235): 3.94e-23: 106: 14.44		CUL5_HUMAN (25-768): 0: 597: 23.77