HitPredict

Interactor 1: HNRPR (O43390)
Heterogeneous nuclear ribonucleoprotein R (hnRNP R)
Gene: HNRNPR

Interactor 2: LARP7 (Q4G0J3)
La-related protein 7 (La ribonucleoprotein domain family member 7) (hLARP7) (P-TEFb-interaction protein for 7SK stability) (PIP7S)
Gene: LARP7

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.66	1.00	0.817

Property	Details
Experiments	26725010, 29845934, 18281698
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	La~RRM_1, RRM_1~RRM_1
Common GO terms	GO:0003723 - RNA binding GO:0003729 - mRNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0006397 - mRNA processing and 1 others more... GO:1990904 - ribonucleoprotein complex
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 633 Hs			1 582
+	Hs
		235888 HNRPQ_HUMAN (3-633): 1.1e-116: 363: 78.17		LARP7_HUMAN (1-582): 1.26e-127: 388: 100.00
+	Hs
		202148 HNRPR_HUMAN (1-633): 1.8e-124: 383: 100.00		PABP4_HUMAN (1-208): 8.15e-41: 158: 11.98
+	Hs
		235835 HNRPQ_HUMAN (3-633): 1.1e-116: 363: 78.17		PABP4_HUMAN (1-208): 8.15e-41: 158: 11.98
+	Hs
		235683 HNRPQ_HUMAN (3-633): 1.1e-116: 363: 78.17		PABP1_HUMAN (1-405): 1.94e-40: 157: 10.29
+	Hs
		235921 HNRPQ_HUMAN (3-633): 1.1e-116: 363: 78.17		LARP4_HUMAN (22-216): 3.23e-40: 157: 21.32
+	Hs
		202248 HNRPR_HUMAN (1-633): 1.8e-124: 383: 100.00		PABP5_HUMAN (12-206): 7.64e-32: 128: 14.15
+	Hs
		235981 HNRPQ_HUMAN (3-633): 1.1e-116: 363: 78.17		LAR4B_HUMAN (2-216): 8.48e-36: 145: 17.02
+	Hs
		236105 HNRPQ_HUMAN (3-633): 1.1e-116: 363: 78.17		RBM28_HUMAN (40-343): 2.97e-23: 106: 13.84
+	Mm
		857343 HNRPQ_MOUSE (3-633): 2.52e-116: 362: 78.17		TIA1_MOUSE (120-325): 5.06e-24: 106: 13.94
+	Hs
		202181 HNRPR_HUMAN (1-633): 1.8e-124: 383: 100.00		ELAV1_HUMAN (92-211): 7.72e-13: 71.9: 22.50
+	Hs
		47770 RBM47_HUMAN (114-563): 1.08e-88: 289: 45.03		PABP4_HUMAN (1-208): 8.15e-41: 158: 11.98
+	Hs
		47742 RBM47_HUMAN (114-563): 1.08e-88: 289: 45.03		PABP1_HUMAN (1-405): 1.94e-40: 157: 10.29
+	Hs
		47799 RBM47_HUMAN (114-563): 1.08e-88: 289: 45.03		LARP4_HUMAN (22-216): 3.23e-40: 157: 21.32
+	Mm
		857321 Q3UZI0_MOUSE (53-633): 5.98e-106: 334: 98.45		TIA1_MOUSE (120-325): 5.06e-24: 106: 13.94
+	Hs
		235877 HNRPQ_HUMAN (3-633): 1.1e-116: 363: 78.17		ELAV1_HUMAN (92-211): 7.72e-13: 71.9: 22.50
+	Hs
		47827 RBM47_HUMAN (114-563): 1.08e-88: 289: 45.03		LAR4B_HUMAN (2-216): 8.48e-36: 145: 17.02
+	Mm
		936683 HNRPQ_MOUSE (3-633): 2.52e-116: 362: 78.17		ELAV1_MOUSE (92-211): 6.43e-13: 71.9: 22.50
+	Hs
		47798 RBM47_HUMAN (114-563): 1.08e-88: 289: 45.03		LARP1_HUMAN (29-114): 6.35e-13: 73.8: 40.23
+	Hs
		47781 RBM47_HUMAN (114-563): 1.08e-88: 289: 45.03		ELAV1_HUMAN (92-211): 7.72e-13: 71.9: 22.50
+	Hs
		474021 PAB4L_HUMAN (166-433): 5.14e-55: 193: 21.20		PABP4_HUMAN (1-208): 8.15e-41: 158: 11.98