HitPredict

Interactor 1: HNRPR (O43390)
Heterogeneous nuclear ribonucleoprotein R (hnRNP R)
Gene: HNRNPR

Interactor 2: IF2B1 (Q9NZI8)
Insulin-like growth factor 2 mRNA-binding protein 1 (IGF2 mRNA-binding protein 1) (IMP-1) (IMP1) (Coding region determinant-binding protein) (CRD-BP) (IGF-II mRNA-binding protein 1) (VICKZ family member 1) (Zipcode-binding protein 1) (ZBP-1)
Gene: IGF2BP1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	1.00	0.691

Property	Details
Experiments	35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	RRM_1~RRM_1
Common GO terms	GO:0003723 - RNA binding GO:0003729 - mRNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:1990904 - ribonucleoprotein complex
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 633 Hs			1 577
+	Hs
		127953 HNRPQ_HUMAN (3-633): 1.1e-116: 363: 78.17		IF2B3_HUMAN (1-577): 4.61e-149: 443: 71.85
+	Hs
		236111 HNRPQ_HUMAN (3-633): 1.1e-116: 363: 78.17		IF2B1_HUMAN (1-577): 4.69e-147: 437: 100.00
+	Hs
		47718 RBM47_HUMAN (114-563): 1.08e-88: 289: 45.03		IF2B3_HUMAN (1-577): 4.61e-149: 443: 71.85
+	Hs
		47887 RBM47_HUMAN (114-563): 1.08e-88: 289: 45.03		IF2B1_HUMAN (1-577): 4.69e-147: 437: 100.00
+	Xl
		251139 EPABA_XENLA (155-608): 8.26e-48: 179: 15.87		IF23A_XENLA (1-577): 1.61e-140: 421: 73.06
+	Hs
		128165 PABP4_HUMAN (69-235): 3.94e-23: 106: 14.44		IF2B3_HUMAN (1-577): 4.61e-149: 443: 71.85
+	Hs
		202177 HNRPR_HUMAN (1-633): 1.8e-124: 383: 100.00		PCBP2_HUMAN (407-575): 6.35e-44: 162: 27.43
+	Hs
		202243 HNRPR_HUMAN (1-633): 1.8e-124: 383: 100.00		FUBP1_HUMAN (118-353): 1.13e-15: 82.3: 14.01
+	Hs
		236155 HNRPQ_HUMAN (3-633): 1.1e-116: 363: 78.17		IF2B2_HUMAN (79-477): 2.19e-19: 93.9: 14.84
+	Hs
		202176 HNRPR_HUMAN (1-633): 1.8e-124: 383: 100.00		PCBP1_HUMAN (476-574): 1.53e-12: 71: 17.17
+	Hs
		236016 HNRPQ_HUMAN (3-633): 1.1e-116: 363: 78.17		FUBP3_HUMAN (190-413): 5.36e-18: 89.3: 18.25
+	Hs
		235999 HNRPQ_HUMAN (3-633): 1.1e-116: 363: 78.17		FUBP1_HUMAN (118-353): 1.13e-15: 82.3: 14.01
+	Hs
		235871 HNRPQ_HUMAN (3-633): 1.1e-116: 363: 78.17		PCBP1_HUMAN (476-574): 1.53e-12: 71: 17.17
+	Hs
		47908 RBM47_HUMAN (114-563): 1.08e-88: 289: 45.03		IF2B2_HUMAN (79-477): 2.19e-19: 93.9: 14.84
+	Hs
		47843 RBM47_HUMAN (114-563): 1.08e-88: 289: 45.03		FUBP3_HUMAN (190-413): 5.36e-18: 89.3: 18.25
+	Hs
		47779 RBM47_HUMAN (114-563): 1.08e-88: 289: 45.03		PCBP1_HUMAN (476-574): 1.53e-12: 71: 17.17
+	Hs
		47757 RBM47_HUMAN (114-563): 1.08e-88: 289: 45.03		PCBP3_HUMAN (65-270): 1.9e-09: 61.5: 15.31
+	Hs
		1273078 A1CF_HUMAN (122-521): 4.37e-75: 253: 44.06		FUBP2_HUMAN (118-416): 2.4e-14: 78.1: 15.89
+	Mm
		888827 RBM47_MOUSE (111-532): 2.67e-67: 232: 46.12		PCBP1_MOUSE (476-574): 1.53e-12: 71: 17.17
+	Zm
		32257 B4F9N8_MAIZE (161-418): 9.5e-41: 156: 35.34		A0A1D6KS04_MAIZE (184-571): 3.64e-17: 87.3: 12.28