HitPredict

Interactor 1: PRPF3 (O43395)
U4/U6 small nuclear ribonucleoprotein Prp3 (Pre-mRNA-splicing factor 3) (hPrp3) (U4/U6 snRNP 90 kDa protein)
Gene: PRPF3

Interactor 2: PRPF3 (O43395)
U4/U6 small nuclear ribonucleoprotein Prp3 (Pre-mRNA-splicing factor 3) (hPrp3) (U4/U6 snRNP 90 kDa protein)
Gene: PRPF3

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.66 1.00 0.817

The method score is based on:

Property Details
Experiments 16723661, 22365833
Identification Methods two hybrid, affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains DUF1115~PRP3, DUF1115~DUF1115, PWI~PWI
Common GO terms GO:0000244 - spliceosomal tri-snRNP complex assembly
GO:0000375 - RNA splicing, via transesterification reactions
GO:0000398 - mRNA splicing, via spliceosome
GO:0003723 - RNA binding
GO:0005634 - nucleus
and 9 others

more...
Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 683
Hs

1 683
+ Dm
+ Sc

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024