HitPredict

Interactor 1: PRPF3 (O43395)
U4/U6 small nuclear ribonucleoprotein Prp3 (Pre-mRNA-splicing factor 3) (hPrp3) (U4/U6 snRNP 90 kDa protein)
Gene: PRPF3

Interactor 2: PRP6 (O94906)
Pre-mRNA-processing factor 6 (Androgen receptor N-terminal domain-transactivating protein 1) (ANT-1) (PRP6 homolog) (U5 snRNP-associated 102 kDa protein) (U5-102 kDa protein)
Gene: PRPF6

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.77 0.60 0.681

The method score is based on:

Property Details
Experiments 28514442, 33961781, 16723661
Identification Methods affinity chromatography technology, pull down, anti tag coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000244 - spliceosomal tri-snRNP complex assembly
GO:0000375 - RNA splicing, via transesterification reactions
GO:0000398 - mRNA splicing, via spliceosome
GO:0003723 - RNA binding
GO:0005634 - nucleus
and 6 others

more...
Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 683
Hs

1 941
+ Sp
+ Sc

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024