HitPredict

Interactor 1: PRPF3 (O43395)
U4/U6 small nuclear ribonucleoprotein Prp3 (Pre-mRNA-splicing factor 3) (hPrp3) (U4/U6 snRNP 90 kDa protein)
Gene: PRPF3

Interactor 2: RSMB (P14678)
Small nuclear ribonucleoprotein-associated proteins B and B' (snRNP-B) (Sm protein B/B') (Sm-B/B') (SmB/B')
Gene: SNRPB

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.75 1.00 0.871

The method score is based on:

Property Details
Experiments 28514442, 33961781, 35271311
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains DUF1115~LSM
Common GO terms GO:0000398 - mRNA splicing, via spliceosome
GO:0003723 - RNA binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005681 - spliceosomal complex
and 4 others

more...
Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 683
Hs

1 240
+ Hs
+ Sc

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024