HitPredict - High confidence protein-protein interactions

Interactor 1: PRPF3 (O43395)
U4/U6 small nuclear ribonucleoprotein Prp3 (Pre-mRNA-splicing factor 3) (hPrp3) (U4/U6 snRNP 90 kDa protein)
Gene: PRPF3

Interactor 2: NH2L1 (P55769)
NHP2-like protein 1 (High mobility group-like nuclear protein 2 homolog 1) (OTK27) (SNU13 homolog) (hSNU13) (U4/U6.U5 small nuclear ribonucleoprotein SNU13) (U4/U6.U5 tri-snRNP 15.5 kDa protein) [Cleaved into: NHP2-like protein 1, N-terminally processed]
Gene: SNU13

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.90	0.819

Method score

Annotation score

Interaction score

0.74

0.90

0.819

Property	Details
Experiments	16723661, 28514442, 33961781
Identification Methods	two hybrid, affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	direct interaction, physical association, association

Property

Details

Experiments

16723661, 28514442, 33961781

Identification Methods

two hybrid, affinity chromatography technology, anti tag coimmunoprecipitation

Interaction Type

direct interaction, physical association, association

Property	Details
Interacting Pfam domains	PRP3~Ribosomal_L7Ae
Common GO terms	GO:0000398 - mRNA splicing, via spliceosome GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0046540 - U4/U6 x U5 tri-snRNP complex and 1 others more... GO:0071005 - U2-type precatalytic spliceosome
Homologous interactions	0

Property

Details

Interacting Pfam domains

PRP3~Ribosomal_L7Ae

Common GO terms

GO:0000398 - mRNA splicing, via spliceosome
GO:0003723 - RNA binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0046540 - U4/U6 x U5 tri-snRNP complex
and 1 others

more...

Homologous interactions