HitPredict

Interactor 1: TXNL1 (O43396)
Thioredoxin-like protein 1 (32 kDa thioredoxin-related protein)
Gene: TXNL1

Interactor 2: TAU (P10636)
Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau)
Gene: MAPT

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.50	0.60	0.552

Property	Details
Experiments	26269332, 35063084
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 289 Hs			1 758
+	Hs
		497523 ERP44_HUMAN (8-285): 3.1e-41: 148: 15.57		TAU_HUMAN (1-758): 3.6e-89: 298: 100.00
+	Hs
		495446 THIO_HUMAN (4-107): 4.64e-42: 142: 40.39		TAU_HUMAN (1-758): 3.6e-89: 298: 100.00
+	Hs
		497573 PITH1_HUMAN (111-275): 4.64e-40: 140: 26.32		TAU_HUMAN (1-758): 3.6e-89: 298: 100.00
+	Hs
		497310 TXND5_HUMAN (3-109): 1.55e-30: 120: 19.64		TAU_HUMAN (1-758): 3.6e-89: 298: 100.00
+	Hs
		497046 PDIA6_HUMAN (5-158): 2.41e-30: 119: 15.63		TAU_HUMAN (1-758): 3.6e-89: 298: 100.00
+	Hs
		496390 PDIA3_HUMAN (5-116): 2.37e-22: 98.3: 15.25		TAU_HUMAN (1-758): 3.6e-89: 298: 100.00
+	Hs
		496945 PDIA2_HUMAN (5-105): 1.26e-20: 93.3: 16.82		TAU_HUMAN (1-758): 3.6e-89: 298: 100.00
+	Hs
		423114 PDIA1_HUMAN (5-105): 1.71e-20: 92.9: 17.76		TAU_HUMAN (1-758): 3.6e-89: 298: 100.00
+	Hs
		1243836 ERP44_HUMAN (8-285): 3.1e-41: 148: 15.57		KMT2C_HUMAN (83-649): 6.28e-09: 61.8: 12.91
+	Dm
		1359509 THIO2_DROME (4-107): 3.25e-38: 132: 36.19		Q9VLS7_DROME (62-753): 1.93e-12: 73.2: 9.96