HitPredict

Interactor 1: TXNL1 (O43396)
Thioredoxin-like protein 1 (32 kDa thioredoxin-related protein)
Gene: TXNL1

Interactor 2: AFAD (P55196)
Afadin (ALL1-fused gene from chromosome 6 protein) (Protein AF-6) (Afadin adherens junction formation factor)
Gene: AFDN

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	34079125
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 289 Hs			1 1824
+	Mm
		1143427 TXNL1_MOUSE (1-289): 6.81e-94: 280: 98.62		DLG4_MOUSE (1002-1238): 8.46e-28: 123: 17.51
+	Hs
		671933 PDIA3_HUMAN (5-116): 2.37e-22: 98.3: 15.25		KI13B_HUMAN (184-691): 5.1e-66: 250: 12.64
+	Hs
		1066141 PDIA6_HUMAN (5-158): 2.41e-30: 119: 15.63		KIF14_HUMAN (179-624): 8.03e-59: 227: 18.67
+	Hs
		671817 PDIA3_HUMAN (5-116): 2.37e-22: 98.3: 15.25		KIF14_HUMAN (179-624): 8.03e-59: 227: 18.67
+	Hs
		531836 PDIA4_HUMAN (3-115): 1.12e-20: 93.7: 18.33		KIF14_HUMAN (179-624): 8.03e-59: 227: 18.67
+	Hs
		423235 PDIA1_HUMAN (5-105): 1.71e-20: 92.9: 17.76		KIF14_HUMAN (179-624): 8.03e-59: 227: 18.67
+	Mm
		498177 THIO_MOUSE (4-107): 3.44e-37: 129: 40.39		DLG4_MOUSE (1002-1238): 8.46e-28: 123: 17.51
+	Mm
		1111999 Q3TML0_MOUSE (5-158): 3.98e-30: 119: 15.63		DLG4_MOUSE (1002-1238): 8.46e-28: 123: 17.51
+	Dm
		113682 TXND5_DROME (5-276): 1.33e-36: 136: 12.94		M9NFI9_DROME (1002-1092): 6.19e-22: 106: 38.95
+	Mm
		653438 PDIA3_MOUSE (5-116): 9.01e-22: 96.4: 15.25		DLG4_MOUSE (1002-1238): 8.46e-28: 123: 17.51
+	Hs
		531825 PDIA4_HUMAN (3-115): 1.12e-20: 93.7: 18.33		SCRIB_HUMAN (989-1133): 4.27e-22: 106: 26.85