HitPredict

Interactor 1: EMC8 (O43402)
ER membrane protein complex subunit 8 (Neighbor of COX4) (Protein FAM158B)
Gene: EMC8

Interactor 2: EMC5 (Q8N4V1)
ER membrane protein complex subunit 5 (Membrane magnesium transporter 1) (Transmembrane protein 32)
Gene: MMGT1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.86	1.00	0.932

Property	Details
Experiments	22119785, 26496610, 27342126, 33961781, 35271311
Identification Methods	affinity chromatography technology, pull down, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	MMgT~UPF0172
Common GO terms	GO:0005789 - endoplasmic reticulum membrane GO:0005794 - Golgi apparatus GO:0016020 - membrane GO:0045050 - protein insertion into ER membrane by stop-transfer membrane-anchor sequence GO:0071816 - tail-anchored membrane protein insertion into ER membrane and 1 others more... GO:0072546 - EMC complex
Homologous interactions	1

Homologous interactions

Color coding for hit scores

	1 210 Hs			1 131
+	Hs
		1234004 EMC9_HUMAN (1-208): 1.28e-88: 261: 43.75		EMC5_HUMAN (1-131): 1.47e-67: 201: 100.00