HitPredict

Interactor 1: P52K (O43422)
52 kDa repressor of the inhibitor of the protein kinase (p52rIPK) (58 kDa interferon-induced protein kinase-interacting protein) (p58IPK-interacting protein) (Death-associated protein 4) (THAP domain-containing protein 0) (THAP domain-containing protein 12)
Gene: THAP12

Interactor 2: SRSF1 (Q07955)
Serine/arginine-rich splicing factor 1 (Alternative-splicing factor 1) (ASF-1) (Splicing factor, arginine/serine-rich 1) (pre-mRNA-splicing factor SF2, P33 subunit)
Gene: SRSF1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 761 Hs			1 248
+	Hs
		203128 P52K_HUMAN (1-761): 0: 725: 100.00		SRSF5_HUMAN (14-183): 8.03e-61: 194: 41.48
+	Hs
		203129 P52K_HUMAN (1-761): 0: 725: 100.00		SRSF6_HUMAN (17-200): 2.58e-57: 187: 40.51
+	Hs
		203122 P52K_HUMAN (1-761): 0: 725: 100.00		SRSF4_HUMAN (17-243): 1.36e-49: 171: 37.66
+	Hs
		203118 P52K_HUMAN (1-761): 0: 725: 100.00		SRSF3_HUMAN (15-99): 9.33e-28: 105: 43.53
+	Hs
		203134 P52K_HUMAN (1-761): 0: 725: 100.00		SRSF7_HUMAN (14-105): 7.34e-23: 94.8: 40.22
+	Zm
		34996 A0A1D6LGW2_MAIZE (107-662): 1.27e-133: 419: 20.00		B4G0Q5_MAIZE (10-227): 1.12e-22: 97.8: 14.29
+	Zm
		13170 A0A1D6FR70_MAIZE (296-575): 4.8e-60: 223: 20.27		A0A1D6I0G1_MAIZE (123-203): 4.33e-11: 64.2: 20.46
+	Hs
		474031 THAP3_HUMAN (1-88): 1.83e-24: 104: 30.77		PAB4L_HUMAN (17-92): 5.07e-19: 86.6: 19.48