HitPredict

Interactor 1: P52K (O43422)
52 kDa repressor of the inhibitor of the protein kinase (p52rIPK) (58 kDa interferon-induced protein kinase-interacting protein) (p58IPK-interacting protein) (Death-associated protein 4) (THAP domain-containing protein 0) (THAP domain-containing protein 12)
Gene: THAP12

Interactor 2: STK4 (Q13043)
Serine/threonine-protein kinase 4 (EC 2.7.11.1) (Mammalian STE20-like protein kinase 1) (MST-1) (STE20-like kinase MST1) (Serine/threonine-protein kinase Krs-2) [Cleaved into: Serine/threonine-protein kinase 4 37kDa subunit (MST1/N); Serine/threonine-protein kinase 4 18kDa subunit (MST1/C)]
Gene: STK4

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.68	0.60	0.639

Property	Details
Experiments	12384512, 24255178
Identification Methods	affinity chromatography technology, pull down, anti tag coimmunoprecipitation
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0007165 - signal transduction
Homologous interactions	3

Homologous interactions

Color coding for hit scores

	1 761 Hs			1 487
+	Hs
		203125 P52K_HUMAN (1-761): 0: 725: 100.00		STK3_HUMAN (1-487): 2.36e-147: 432: 72.47
+	Mm
		949390 EPMIP_MOUSE (126-671): 1.67e-101: 326: 13.80		TNIK_MOUSE (8-309): 1.1e-73: 254: 44.80
+	Hs
		1264367 THAP4_HUMAN (1-108): 1.8e-24: 110: 27.43		TNIK_HUMAN (8-309): 2.1e-73: 254: 44.80