HitPredict

Interactor 1: SYNJ1 (O43426)
Synaptojanin-1 (EC 3.1.3.36) (Synaptic inositol 1,4,5-trisphosphate 5-phosphatase 1)
Gene: SYNJ1

Interactor 2: SRBS2 (O94875)
Sorbin and SH3 domain-containing protein 2 (Arg-binding protein 2) (ArgBP2) (Arg/Abl-interacting protein 2) (Sorbin)
Gene: SORBS2

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.614

Property	Details
Experiments	35914814, 11292345
Identification Methods	two hybrid, pull down, phage display
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0048471 - perinuclear region of cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1573 Hs			1 1100
+	Rn
		192744 SYNJ1_RAT (1-1573): 0: 1317: 88.27		SRBS2_RAT (1-1100): 0: 751: 87.30
+	Hs
		203191 SYNJ1_HUMAN (1-1573): 0: 1356: 100.00		VINEX_HUMAN (536-1100): 1.68e-35: 146: 25.65
+	Hs
		203228 SYNJ1_HUMAN (1-1573): 0: 1356: 100.00		ITSN1_HUMAN (131-1070): 1.55e-28: 126: 10.05
+	Hs
		203218 SYNJ1_HUMAN (1-1573): 0: 1356: 100.00		GRB2_HUMAN (743-923): 8.99e-28: 114: 17.90
+	Hs
		203224 SYNJ1_HUMAN (1-1573): 0: 1356: 100.00		MYO1E_HUMAN (874-1100): 1.36e-21: 103: 16.00
+	Hs
		203230 SYNJ1_HUMAN (1-1573): 0: 1356: 100.00		SH319_HUMAN (852-921): 3.89e-13: 75.9: 37.50
+	Hs
		203208 SYNJ1_HUMAN (1-1573): 0: 1356: 100.00		NCK1_HUMAN (867-975): 2.49e-13: 75.1: 20.54
+	Hs
		203241 SYNJ1_HUMAN (1-1573): 0: 1356: 100.00		SH3K1_HUMAN (942-1100): 2.45e-12: 73.2: 30.86
+	Hs
		203250 SYNJ1_HUMAN (1-1573): 0: 1356: 100.00		SRBS1_HUMAN (713-921): 7.81e-12: 72: 16.90
+	Hs
		166056 SYNJ2_HUMAN (1-1418): 0: 1118: 41.56		ITSN2_HUMAN (345-1100): 1.94e-53: 207: 13.12
+	Hs
		166049 SYNJ2_HUMAN (1-1418): 0: 1118: 41.56		ITSN1_HUMAN (131-1070): 1.55e-28: 126: 10.05
+	Hs
		166042 SYNJ2_HUMAN (1-1418): 0: 1118: 41.56		GRB2_HUMAN (743-923): 8.99e-28: 114: 17.90
+	Hs
		166030 SYNJ2_HUMAN (1-1418): 0: 1118: 41.56		NCK1_HUMAN (867-975): 2.49e-13: 75.1: 20.54
+	Hs
		166055 SYNJ2_HUMAN (1-1418): 0: 1118: 41.56		SH3K1_HUMAN (942-1100): 2.45e-12: 73.2: 30.86
+	Hs
		166060 SYNJ2_HUMAN (1-1418): 0: 1118: 41.56		CD2AP_HUMAN (944-1100): 5.5e-12: 72: 29.70
+	Dm
		112574 Q5U0V7_DROME (1-1130): 0: 1048: 48.47		M9ND00_DROME (147-956): 1.01e-32: 140: 12.92
+	Ce
		104677 SYNJ_CAEEL (5-1160): 0: 938: 39.64		SRBS1_CAEEL (711-1023): 4.14e-26: 118: 23.17
+	Ce
		105280 SYNJ_CAEEL (5-1160): 0: 938: 39.64		Q95PW9_CAEEL (941-1100): 4.45e-23: 104: 26.16
+	Ce
		105281 SYNJ_CAEEL (5-1160): 0: 938: 39.64		Q9U2T9_CAEEL (916-1100): 2.24e-19: 96.5: 21.18
+	Ce
		105207 SYNJ_CAEEL (5-1160): 0: 938: 39.64		G5ECK4_CAEEL (868-996): 3.34e-12: 73.2: 35.56