HitPredict

Interactor 1: SYNJ1 (O43426)
Synaptojanin-1 (EC 3.1.3.36) (Synaptic inositol 1,4,5-trisphosphate 5-phosphatase 1)
Gene: SYNJ1

Interactor 2: TAU (P10636)
Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau)
Gene: MAPT

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.50	0.60	0.552

Property	Details
Experiments	26402096, 35063084
Identification Methods	anti bait coimmunoprecipitation, anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005829 - cytosol GO:0017124 - SH3 domain binding
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 1573 Hs			1 758
+	Rn
		582007 SYNJ1_RAT (1-1573): 0: 1317: 88.27		TAU_RAT (1-758): 4.86e-75: 260: 71.47
+	Rn
		94231 SYNJ1_RAT (1-1573): 0: 1317: 88.27		F1LST4_RAT (1-757): 8.59e-75: 260: 71.56
+	Mm
		88453 D3Z656_MOUSE (1-1573): 0: 1312: 88.66		TAU_MOUSE (1-758): 1.4e-69: 244: 70.17
+	Dm
		1137153 Q5U0V7_DROME (1-1130): 0: 1048: 48.47		Q9VLS7_DROME (62-753): 1.93e-12: 73.2: 9.96
+	Hs
		497660 SAC1_HUMAN (12-521): 1.37e-172: 532: 27.07		TAU_HUMAN (1-758): 3.6e-89: 298: 100.00