Interactor 1: IF4G3 (O43432)
Eukaryotic translation initiation factor 4 gamma 3 (eIF-4-gamma 3) (eIF-4G 3) (eIF4G 3) (eIF-4-gamma II) (eIF4GII)
Gene: EIF4G3

Interactor 2: IF4E (P06730)
Eukaryotic translation initiation factor 4E (eIF-4E) (eIF4E) (eIF-4F 25 kDa subunit) (mRNA cap-binding protein)
Gene: EIF4E

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.94 0.60 0.753

The method score is based on:

Property Details
Experiments 9418880, 26186194, 28514442, 24981860, 33961781, 20212144, 21191102, 16189514
Identification Methods affinity chromatography technology, far western blotting, nuclear magnetic resonance, pull down, two hybrid pooling approach, anti tag coimmunoprecipitation, tandem affinity purification
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000339 - RNA cap binding
GO:0003723 - RNA binding
GO:0003743 - translation initiation factor activity
GO:0005829 - cytosol
GO:0006413 - translational initiation
and 1 others

more...

Homologous interactions 18

Homologous interactions

Color coding for hit scores

1 1585
Hs

1 217
+ Mm
+ Hs
+ Dm
+ Dm
+ Dm
+ Dm
+ Dm
+ Dm
+ Dm
+ Dm
+ Ce
+ At
+ At
+ At
+ Sc
+ Sc
+ Mm
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024