HitPredict

Interactor 1: MTG8R (O43439)
Protein CBFA2T2 (ETO homologous on chromosome 20) (MTG8-like protein) (MTG8-related protein 1) (Myeloid translocation-related protein 1) (p85)
Gene: CBFA2T2

Interactor 2: MTG16 (O75081)
Protein CBFA2T3 (MTG8-related protein 2) (Myeloid translocation gene on chromosome 16 protein) (hMTG16) (Zinc finger MYND domain-containing protein 4)
Gene: CBFA2T3

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.84	1.00	0.918

Property	Details
Experiments	32296183, 26593974, 12242670, 33961781, 27281218
Identification Methods	two hybrid, affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	direct interaction, physical association, association

Property	Details
Interacting Pfam domains	NHR2~NHR2, TAFH~TAFH, zf-MYND~zf-MYND
Common GO terms	GO:0003714 - transcription corepressor activity GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0006351 - DNA-templated transcription GO:0045892 - negative regulation of DNA-templated transcription and 1 others more... GO:0046872 - metal ion binding
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 604 Hs			1 653
+	Hs
		253974 MTG8_HUMAN (22-601): 0: 836: 63.40		MTG16_HUMAN (1-653): 0: 1003: 100.00
+	Hs
		203448 MTG8R_HUMAN (1-604): 0: 936: 100.00		MTG8_HUMAN (54-653): 0: 846: 69.67
+	Hs
		203429 MTG8R_HUMAN (1-604): 0: 936: 100.00		MTG8R_HUMAN (53-641): 0: 841: 57.64
+	Hs
		987407 MTG8_HUMAN (22-601): 0: 836: 63.40		MTG8_HUMAN (54-653): 0: 846: 69.67
+	Hs
		263405 DEAF1_HUMAN (483-548): 8e-26: 113: 39.39		DEAF1_HUMAN (525-595): 1.11e-25: 113: 37.66