HitPredict

Interactor 1: SUV91 (O43463)
Histone-lysine N-methyltransferase SUV39H1 (EC 2.1.1.355) (Histone H3-K9 methyltransferase 1) (H3-K9-HMTase 1) (Lysine N-methyltransferase 1A) (Position-effect variegation 3-9 homolog) (Suppressor of variegation 3-9 homolog 1) (Su(var)3-9 homolog 1)
Gene: SUV39H1

Interactor 2: CBX3 (Q13185)
Chromobox protein homolog 3 (HECH) (Heterochromatin protein 1 homolog gamma) (HP1 gamma) (Modifier 2 protein)
Gene: CBX3

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.86 1.00 0.931

The method score is based on:

Property Details
Experiments 27705803, 24981860, 32296183, 33961781, unassigned1304
Identification Methods affinity chromatography technology, two hybrid, tandem affinity purification, two hybrid prey pooling approach, two hybrid array, validated two hybrid, anti tag coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains Chromo~Chromo
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000775 - chromosome, centromeric region
GO:0000792 - heterochromatin
GO:0003682 - chromatin binding
GO:0005634 - nucleus
and 4 others

more...
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 412
Hs

1 183
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Last updated: 15 Jul 2024