HitPredict

Interactor 1: SUV91 (O43463)
Histone-lysine N-methyltransferase SUV39H1 (EC 2.1.1.355) (Histone H3-K9 methyltransferase 1) (H3-K9-HMTase 1) (Lysine N-methyltransferase 1A) (Position-effect variegation 3-9 homolog) (Suppressor of variegation 3-9 homolog 1) (Su(var)3-9 homolog 1)
Gene: SUV39H1

Interactor 2: H32 (Q71DI3)
Histone H3.2 (H3-clustered histone 13) (H3-clustered histone 14) (H3-clustered histone 15) (Histone H3/m) (Histone H3/o)
Gene: H3C15

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	1.00	0.647

Property	Details
Experiments	14985713
Identification Methods	enzymatic study
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	Histone~SET
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0006325 - chromatin organization
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 412 Hs			1 136
+	Hs
		203659 SUV91_HUMAN (1-412): 2.55e-163: 467: 100.00		H31_HUMAN (1-136): 1.98e-62: 189: 99.27
+	Hs
		203664 SUV91_HUMAN (1-412): 2.55e-163: 467: 100.00		H33_HUMAN (1-136): 1.59e-61: 186: 97.06
+	Hs
		203706 SUV91_HUMAN (1-412): 2.55e-163: 467: 100.00		H37_HUMAN (1-136): 3.26e-59: 181: 97.06
+	Hs
		203711 SUV91_HUMAN (1-412): 2.55e-163: 467: 100.00		H3C_HUMAN (1-136): 8.83e-59: 179: 94.12
+	Hs
		935237 SUV92_HUMAN (2-411): 3.41e-148: 428: 57.45		H31_HUMAN (1-136): 1.98e-62: 189: 99.27
+	Hs
		952627 SUV92_HUMAN (2-411): 3.41e-148: 428: 57.45		H33_HUMAN (1-136): 1.59e-61: 186: 97.06
+	Dm
		356073 SUV39_DROME (26-412): 1.78e-88: 282: 33.26		H3_DROME (1-136): 3.73e-61: 186: 100.00
+	Mm
		952777 EHMT2_MOUSE (81-408): 6.88e-84: 280: 31.58		H33_MOUSE (1-136): 1.59e-61: 186: 97.06
+	Hs
		935126 EHMT2_HUMAN (81-408): 1.21e-82: 276: 31.58		H31_HUMAN (1-136): 1.98e-62: 189: 99.27
+	Hs
		1086279 EHMT2_HUMAN (81-408): 1.21e-82: 276: 31.58		H31T_HUMAN (1-136): 8.3e-62: 187: 96.32
+	Hs
		1174632 EHMT2_HUMAN (81-408): 1.21e-82: 276: 31.58		H32_HUMAN (1-136): 3.73e-61: 186: 100.00
+	Hs
		952553 EHMT2_HUMAN (81-408): 1.21e-82: 276: 31.58		H33_HUMAN (1-136): 1.59e-61: 186: 97.06
+	Hs
		935251 EHMT1_HUMAN (112-408): 1.23e-80: 271: 32.13		H31_HUMAN (1-136): 1.98e-62: 189: 99.27
+	Hs
		1086320 EHMT1_HUMAN (112-408): 1.23e-80: 271: 32.13		H31T_HUMAN (1-136): 8.3e-62: 187: 96.32
+	Hs
		952633 EHMT1_HUMAN (112-408): 1.23e-80: 271: 32.13		H33_HUMAN (1-136): 1.59e-61: 186: 97.06
+	At
		886462 SUVH4_ARATH (86-412): 6.4e-81: 262: 22.89		H33_ARATH (1-136): 4.35e-62: 188: 96.32
+	Hs
		935276 ASH1L_HUMAN (67-409): 1.04e-72: 249: 21.39		H31_HUMAN (1-136): 1.98e-62: 189: 99.27
+	Hs
		952649 ASH1L_HUMAN (67-409): 1.04e-72: 249: 21.39		H33_HUMAN (1-136): 1.59e-61: 186: 97.06
+	Hs
		935204 SETD2_HUMAN (87-411): 1.48e-67: 234: 24.26		H31_HUMAN (1-136): 1.98e-62: 189: 99.27
+	Hs
		828381 EHMT1_HUMAN (112-408): 1.23e-80: 271: 32.13		CENPA_HUMAN (9-133): 2.85e-44: 143: 50.00