Interactor 1: HTRA2 (O43464)
Serine protease HTRA2, mitochondrial (EC 3.4.21.108) (High temperature requirement protein A2) (HtrA2) (Omi stress-regulated endoprotease) (Serine protease 25) (Serine proteinase OMI)
Gene: HTRA2

Interactor 2: LATS1 (O95835)
Serine/threonine-protein kinase LATS1 (EC 2.7.11.1) (Large tumor suppressor homolog 1) (WARTS protein kinase) (h-warts)
Gene: LATS1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.76 0.60 0.678

The method score is based on:

Property Details
Experiments 17130845, 16007220, 22641346
Identification Methods affinity chromatography technology, enzymatic study, pull down
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005634 - nucleus
GO:0005829 - cytosol
GO:0043065 - positive regulation of apoptotic process
Homologous interactions 3

Homologous interactions

Color coding for hit scores

1 458
Hs

1 1130
+ Zm
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024