Interactor 1: HTRA2 (O43464)
Serine protease HTRA2, mitochondrial (EC 3.4.21.108) (High temperature requirement protein A2) (HtrA2) (Omi stress-regulated endoprotease) (Serine protease 25) (Serine proteinase OMI)
Gene: HTRA2
Interactor 2: BIRC6 (Q9NR09)
Baculoviral IAP repeat-containing protein 6 (EC 2.3.2.27) (BIR repeat-containing ubiquitin-conjugating enzyme) (BRUCE) (RING-type E3 ubiquitin transferase BIRC6) (Ubiquitin-conjugating BIR domain enzyme apollon) (APOLLON)
Gene: BIRC6
Species: Homo sapiens
Source: innatedb
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.94 | 0.60 | 0.755 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 36758105, 36758106, 36758104, 15300255, 15781261, 15200957, 31617661, 15507451 |
| Identification Methods | enzymatic study, x-ray crystallography, affinity chromatography technology, fluorescent resonance energy transfer, proximity labelling technology, pull down, anti tag coimmunoprecipitation |
| Interaction Type | direct interaction, association, physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | - |
| Common GO terms | GO:0005634 - nucleus GO:0005829 - cytosol GO:0016020 - membrane |
| Homologous interactions | 10 |
Homologous interactions
Color coding for hit scores 
|
|
|||||||||||||
| + | Mm |   |
 |
|||||||||||
| + | Mm | |
|
|||||||||||
| + | Mm | |
|
|||||||||||
| + | Hs | |
|
|||||||||||
| + | Hs | |
|
|||||||||||
| + | Hs | |
|
|||||||||||
| + | Hs | |
|
|||||||||||
| + | Hs | |
|
|||||||||||
| + | Hs | |
|
|||||||||||
| + | Dm | |
 |
|||||||||||
Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
