Interactor 1: HTRA2 (O43464)
Serine protease HTRA2, mitochondrial (EC 3.4.21.108) (High temperature requirement protein A2) (HtrA2) (Omi stress-regulated endoprotease) (Serine protease 25) (Serine proteinase OMI)
Gene: HTRA2

Interactor 2: DBLOH (Q9NR28)
Diablo IAP-binding mitochondrial protein (Diablo homolog, mitochondrial) (Direct IAP-binding protein with low pI) (Second mitochondria-derived activator of caspase) (Smac) [Cleaved into: Diablo IAP-binding mitochondrial protein, cleaved form]
Gene: DIABLO

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.64 0.60 0.624

The method score is based on:

Property Details
Experiments 32877691, 11606597
Identification Methods proximity labelling technology, far western blotting, affinity chromatography technology
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005739 - mitochondrion
GO:0005758 - mitochondrial intermembrane space
GO:0005829 - cytosol
GO:0009898 - cytoplasmic side of plasma membrane
GO:0035631 - CD40 receptor complex
and 2 others

more...

Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 458
Hs

1 239
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024