Interactor 1: ARK72 (O43488)
Aflatoxin B1 aldehyde reductase member 2 (EC 1.1.1.n11) (AFB1 aldehyde reductase 1) (AFB1-AR 1) (Aldoketoreductase 7) (Succinic semialdehyde reductase) (SSA reductase)
Gene: AKR7A2

Interactor 2: ARK73 (O95154)
Aflatoxin B1 aldehyde reductase member 3 (EC 1.-.-.-) (AFB1 aldehyde reductase 2) (AFB1-AR 2)
Gene: AKR7A3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.93 1.00 0.966

The method score is based on:

Property Details
Experiments 26186194, 28514442, 33961781, 16189514, 32296183, 31515488, unassigned1304
Identification Methods affinity chromatography technology, two hybrid, anti tag coimmunoprecipitation, two hybrid array, two hybrid prey pooling approach, validated two hybrid, two hybrid pooling approach
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains Aldo_ket_red~Aldo_ket_red
Common GO terms GO:0004033 - aldo-keto reductase (NADPH) activity
GO:0005737 - cytoplasm
GO:0005794 - Golgi apparatus
GO:0005829 - cytosol
GO:0006081 - cellular aldehyde metabolic process
and 2 others

more...

Homologous interactions 15

Homologous interactions

Color coding for hit scores

1 359
Hs

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Last updated: 15 Jul 2024