HitPredict

Interactor 1: TGON2 (O43493)
Trans-Golgi network integral membrane protein 2 (Trans-Golgi network glycoprotein 46) (TGN38 homolog) (hTGN46) (Trans-Golgi network glycoprotein 48) (hTGN48) (Trans-Golgi network glycoprotein 51) (hTGN51) (Trans-Golgi network protein 2)
Gene: TGOLN2

Interactor 2: CRK (P46108)
Adapter molecule crk (Proto-oncogene c-Crk) (p38)
Gene: CRK

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	17474147
Identification Methods	peptide array
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 437 Hs			1 304
+	Hs
		205025 TGON2_HUMAN (1-437): 1.03e-62: 210: 100.00		PLCG1_HUMAN (1-302): 7.99e-27: 112: 15.39
+	Hs
		205251 TGON2_HUMAN (1-437): 1.03e-62: 210: 100.00		GRB2_HUMAN (135-297): 2.78e-25: 102: 15.67
+	Hs
		802854 TENS2_HUMAN (9-345): 1.68e-22: 102: 14.33		CRKL_HUMAN (2-302): 4.5e-57: 187: 48.07
+	Hs
		206084 TGON2_HUMAN (1-437): 1.03e-62: 210: 100.00		ITSN2_HUMAN (189-304): 5.82e-12: 68.3: 11.86
+	Hs
		205008 TGON2_HUMAN (1-437): 1.03e-62: 210: 100.00		NCK1_HUMAN (2-100): 1.55e-10: 63.3: 18.00
+	Hs
		205432 TGON2_HUMAN (1-437): 1.03e-62: 210: 100.00		ITSN1_HUMAN (150-302): 3.02e-10: 63.3: 13.87
+	Hs
		924632 TENS2_HUMAN (9-345): 1.68e-22: 102: 14.33		GRB2_HUMAN (135-297): 2.78e-25: 102: 15.67
+	Hs
		855816 TITIN_HUMAN (18-351): 1.31e-09: 62.9: 10.41		VAV2_HUMAN (2-191): 3.44e-29: 119: 19.74
+	Hs
		554292 MUC1_HUMAN (17-398): 8.52e-13: 72.6: 9.42		GRB2_HUMAN (135-297): 2.78e-25: 102: 15.67
+	Hs
		517796 NFH_HUMAN (76-385): 7.1e-12: 69.5: 13.78		GRB2_HUMAN (135-297): 2.78e-25: 102: 15.67
+	Hs
		203218 SYNJ1_HUMAN (17-393): 3.24e-10: 64.5: 9.60		GRB2_HUMAN (135-297): 2.78e-25: 102: 15.67
+	Hs
		924760 PRG4_HUMAN (86-391): 4.16e-10: 64.1: 8.77		GRB2_HUMAN (135-297): 2.78e-25: 102: 15.67
+	Ce
		136804 UNC89_CAEEL (9-201): 9.94e-10: 63.3: 11.74		VAV_CAEEL (13-194): 4.87e-22: 98.4: 23.94
+	Hs
		203208 SYNJ1_HUMAN (17-393): 3.24e-10: 64.5: 9.60		NCK1_HUMAN (2-100): 1.55e-10: 63.3: 18.00
+	Hs
		203228 SYNJ1_HUMAN (17-393): 3.24e-10: 64.5: 9.60		ITSN1_HUMAN (150-302): 3.02e-10: 63.3: 13.87
+	Hs
		203241 SYNJ1_HUMAN (17-393): 3.24e-10: 64.5: 9.60		SH3K1_HUMAN (114-192): 4.08e-10: 62.5: 22.22