HitPredict

Interactor 1: TGON2 (O43493)
Trans-Golgi network integral membrane protein 2 (Trans-Golgi network glycoprotein 46) (TGN38 homolog) (hTGN46) (Trans-Golgi network glycoprotein 48) (hTGN48) (Trans-Golgi network glycoprotein 51) (hTGN51) (Trans-Golgi network protein 2)
Gene: TGOLN2

Interactor 2: AP2M1 (Q96CW1)
AP-2 complex subunit mu (AP-2 mu chain) (Adaptin-mu2) (Adaptor protein complex AP-2 subunit mu) (Adaptor-related protein complex 2 subunit mu) (Clathrin assembly protein complex 2 mu medium chain) (Clathrin coat assembly protein AP50) (Clathrin coat-associated protein AP50) (HA2 50 kDa subunit) (Plasma membrane adaptor AP-2 50 kDa protein)
Gene: AP2M1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.68	0.60	0.641

Property	Details
Experiments	29568061, 15254094, 10814565
Identification Methods	proximity labelling technology, two hybrid
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0030669 - clathrin-coated endocytic vesicle membrane
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 437 Hs			1 435
+	Hs
		205932 TGON2_HUMAN (1-437): 1.03e-62: 210: 100.00		AP1M1_HUMAN (2-434): 5.69e-170: 484: 38.85
+	Rn
		587329 TGON3_RAT (97-436): 3.48e-34: 132: 40.00		AP2M1_RAT (1-435): 1.03e-178: 507: 100.00
+	Hs
		206195 TGON2_HUMAN (1-437): 1.03e-62: 210: 100.00		AP3M1_HUMAN (1-434): 1.4e-123: 366: 24.66
+	Hs
		203244 SYNJ1_HUMAN (17-393): 3.24e-10: 64.5: 9.60		AP2M1_HUMAN (1-435): 1.03e-178: 507: 100.00
+	Rn
		587328 TGON3_RAT (97-436): 3.48e-34: 132: 40.00		AP3M1_RAT (1-434): 1.09e-122: 364: 24.66
+	Hs
		205756 TGON2_HUMAN (1-437): 1.03e-62: 210: 100.00		STON2_HUMAN (146-433): 1.58e-62: 219: 22.85