HitPredict

Interactor 1: TGON2 (O43493)
Trans-Golgi network integral membrane protein 2 (Trans-Golgi network glycoprotein 46) (TGN38 homolog) (hTGN46) (Trans-Golgi network glycoprotein 48) (hTGN48) (Trans-Golgi network glycoprotein 51) (hTGN51) (Trans-Golgi network protein 2)
Gene: TGOLN2

Interactor 2: RUFY1 (Q96T51)
RUN and FYVE domain-containing protein 1 (FYVE-finger protein EIP1) (La-binding protein 1) (Rab4-interacting protein) (Zinc finger FYVE domain-containing protein 12)
Gene: RUFY1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.78	0.60	0.686

Property	Details
Experiments	26186194, 28514442, 29568061, 35696571
Identification Methods	affinity chromatography technology, proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005768 - endosome
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 437 Hs			1 708
+	Hs
		206193 TGON2_HUMAN (1-437): 1.03e-62: 210: 100.00		FYV1_HUMAN (545-708): 1.05e-38: 156: 25.56
+	Hs
		205109 TGON2_HUMAN (1-437): 1.03e-62: 210: 100.00		MYH9_HUMAN (362-667): 1.39e-14: 80.1: 15.66
+	Hs
		204819 TGON2_HUMAN (1-437): 1.03e-62: 210: 100.00		ROCK2_HUMAN (348-660): 2.44e-10: 66.1: 12.81
+	Hs
		204873 TGON2_HUMAN (1-437): 1.03e-62: 210: 100.00		ZFYV9_HUMAN (639-700): 4.53e-10: 65.5: 41.27
+	Hs
		270636 MYCB2_HUMAN (16-437): 3.13e-46: 173: 14.64		EEA1_HUMAN (326-667): 1.35e-11: 70.4: 11.92
+	Hs
		1035177 TENS2_HUMAN (9-345): 1.68e-22: 102: 14.33		ROCK1_HUMAN (102-638): 4.76e-13: 74.9: 12.96
+	Hs
		1144575 TENS2_HUMAN (9-345): 1.68e-22: 102: 14.33		WDFY3_HUMAN (639-696): 1.25e-10: 67.4: 43.33
+	Dm
		54321 A1Z9J3_DROME (4-388): 4.39e-17: 86.4: 10.69		HRS_DROME (648-707): 5.32e-10: 64.7: 45.16
+	Hs
		551790 TITIN_HUMAN (18-351): 1.31e-09: 62.9: 10.41		DESP_HUMAN (328-650): 9.91e-10: 64.5: 13.41