Interactor 1: TNF12 (O43508)
Tumor necrosis factor ligand superfamily member 12 (APO3 ligand) (TNF-related weak inducer of apoptosis) (TWEAK) [Cleaved into: Tumor necrosis factor ligand superfamily member 12, membrane form; Tumor necrosis factor ligand superfamily member 12, secreted form]
Gene: TNFSF12

Interactor 2: TNR12 (Q9NP84)
Tumor necrosis factor receptor superfamily member 12A (Fibroblast growth factor-inducible immediate-early response protein 14) (FGF-inducible 14) (Tweak-receptor) (TweakR) (CD antigen CD266)
Gene: TNFRSF12A

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.62 0.55 0.585

The method score is based on:

Property Details
Experiments 23750247, 23438059
Identification Methods far western blotting, surface plasmon resonance, enzyme linked immunosorbent assay
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0001525 - angiogenesis
GO:0005886 - plasma membrane
GO:0006915 - apoptotic process
GO:0030154 - cell differentiation
GO:2001238 - positive regulation of extrinsic apoptotic signaling pathway
Homologous interactions 0

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Last updated: 15 Jul 2024