HitPredict

Interactor 1: WIPF1 (O43516)
WAS/WASL-interacting protein family member 1 (Protein PRPL-2) (Wiskott-Aldrich syndrome protein-interacting protein) (WASP-interacting protein)
Gene: WIPF1

Interactor 2: HCK (P08631)
Tyrosine-protein kinase HCK (EC 2.7.10.2) (Hematopoietic cell kinase) (Hemopoietic cell kinase) (p59-HCK/p60-HCK) (p59Hck) (p61Hck)
Gene: HCK

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.46	0.60	0.527

Property	Details
Experiments	12029088
Identification Methods	pull down
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 503 Hs			1 526
+	Hs
		442894 ASAP1_HUMAN (12-437): 1.91e-27: 118: 19.59		HCK_HUMAN (1-526): 0: 635: 100.00
+	Hs
		442816 SOS1_HUMAN (134-459): 8.01e-24: 107: 16.77		HCK_HUMAN (1-526): 0: 635: 100.00
+	Hs
		523197 ASAP1_HUMAN (12-437): 1.91e-27: 118: 19.59		SRC_HUMAN (1-524): 0: 582: 54.51
+	Hs
		206676 WIPF1_HUMAN (1-503): 1.19e-30: 126: 100.00		FYN_HUMAN (22-524): 0: 564: 57.79
+	Hs
		522934 SOS1_HUMAN (134-459): 8.01e-24: 107: 16.77		SRC_HUMAN (1-524): 0: 582: 54.51
+	Hs
		411690 SOS1_HUMAN (134-459): 8.01e-24: 107: 16.77		LCK_HUMAN (23-526): 0: 581: 64.89
+	Hs
		166024 SYNJ2_HUMAN (11-462): 6.97e-28: 120: 15.62		FYN_HUMAN (22-524): 0: 564: 57.79
+	Hs
		412404 ASAP1_HUMAN (12-437): 1.91e-27: 118: 19.59		FYN_HUMAN (22-524): 0: 564: 57.79
+	Hs
		522749 MUC1_HUMAN (3-456): 2.41e-21: 100: 14.19		SRC_HUMAN (1-524): 0: 582: 54.51
+	Hs
		411582 MUC1_HUMAN (3-456): 2.41e-21: 100: 14.19		LCK_HUMAN (23-526): 0: 581: 64.89
+	Hs
		412150 SOS1_HUMAN (134-459): 8.01e-24: 107: 16.77		FYN_HUMAN (22-524): 0: 564: 57.79
+	Hs
		433560 MUC1_HUMAN (3-456): 2.41e-21: 100: 14.19		LYN_HUMAN (22-526): 0: 554: 70.70
+	Hs
		203198 SYNJ1_HUMAN (2-362): 9.7e-09: 60.2: 13.72		LCK_HUMAN (23-526): 0: 581: 64.89
+	Hs
		412433 MYO16_HUMAN (53-377): 6.21e-09: 61: 15.96		FYN_HUMAN (22-524): 0: 564: 57.79
+	Hs
		166023 SYNJ2_HUMAN (11-462): 6.97e-28: 120: 15.62		ABL1_HUMAN (47-523): 1.77e-166: 502: 39.38
+	Hs
		337590 ASAP1_HUMAN (12-437): 1.91e-27: 118: 19.59		ABL1_HUMAN (47-523): 1.77e-166: 502: 39.38
+	Hs
		297808 K0754_HUMAN (1-184): 6.54e-09: 61: 10.71		LYN_HUMAN (22-526): 0: 554: 70.70
+	Hs
		337446 SOS1_HUMAN (134-459): 8.01e-24: 107: 16.77		ABL1_HUMAN (47-523): 1.77e-166: 502: 39.38
+	Hs
		337335 MUC1_HUMAN (3-456): 2.41e-21: 100: 14.19		ABL1_HUMAN (47-523): 1.77e-166: 502: 39.38
+	Hs
		789012 ASAP1_HUMAN (12-437): 1.91e-27: 118: 19.59		TEC_HUMAN (3-520): 3.4e-162: 476: 34.20